Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
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Lee, Yoot-Mo
(College of Pharmacy and CBITRC, Chungbuk National University)
Seong, Min-Jae (College of Pharmacy and CBITRC, Chungbuk National University) Lee, Jae-Woong (College of Pharmacy and CBITRC, Chungbuk National University) Lee, Yong-Kyung (College of Pharmacy and CBITRC, Chungbuk National University) Kim, Tae-Myoung (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Nam, Sang-Yoon (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Kim, Dae-Joong (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Yun, Young-Won (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Kim, Tae-Seong (National Institute of Toxicological Research, Korea Food and Drug Administration) Han, Soon-Young (National Institute of Toxicological Research, Korea Food and Drug Administration) Hong, Jin-Tae (College of Pharmacy and CBITRC, Chungbuk National University) |
1 | Chaban VV, Mayer EA, Ennes HS, Micevych PE. Estradiol inhibits atp-induced intracellular calcium concentration increase in dorsal root ganglia neurons. Neuroscience 2003, 118, 941- 948 DOI ScienceOn |
2 | Guillette LJ Jr, Gross TS, Gross DA, Rooney AA, Percival HF. Gonadal steroidogenesis in vitro from juvenile alligators obtained from contaminated or control lakes. Environ Health Perspect 1995, 103 (Suppl), 31-36 DOI |
3 | Gursoy E, Cardounel A, Kalimi M. The environmental estrogenic compound bisphenol A exerts estrogenic effects on mouse hippocampal (HT-22) cells: neuroprotection against glutamate and amyloid beta protein toxicity. Neurochem Int 2001, 38, 181-186 DOI ScienceOn |
4 | Iida H, Maehara K, Doiguchi M, Mori T, Yamada F. Bisphenol A-induced apoptosis of cultured rat Sertoli cells. Reprod Toxicol 2003, 17, 457-464 DOI ScienceOn |
5 | Ikezuki Y, Tsutsumi O, Takai Y, Kamei Y, Taketani Y. Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure. Hum Reprod 2002, 17, 2839-2841 DOI ScienceOn |
6 |
Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B, Gustafsson JA. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor |
7 |
O'Neill LAJ, Kaltschmidt C. NF- |
8 | Seoung MJ, Shin IC, Lee YM, Son DJ, Song YS, Jeon KH, Kim YB, Lee BJ, Kim DJ, Yun YW, Kim TS, Han SY. Behavior alterations and expression of estrogen receptors in mice exposed to Bisphenol A. J Toxicol Public Health 2004, 20, 67-77 |
9 | Takai Y, Tsutsumi O, Ikezuki Y, Hiroi H, Osuga Y, Momoeda M, Yano T, Taketani Y. Estrogen receptormediated effects of a xenoestrogen, bisphenol A, on preimplantation mouse embryos. Biochem Biophys Res Commun 2000, 270, 918-921 DOI ScienceOn |
10 | Zoubina EV, Smith PG. Expression of estrogen receptors alpha and beta by sympathetic ganglion neurons projecting to the proximal urethra of female rats. J Urol 2003, 169, 382-385 DOI ScienceOn |
11 | Aloisi AM, Della Seta D, Rendo C, Ceccarelli I, Scaramuzzino A, Farabollini F. Exposure to the estrogenic pollutant bisphenol A affects pain behavior induced by subcutaneous formalin injection in male and female rats. Brain Res 2002, 937, 1-7 DOI ScienceOn |
12 | Alessandrini A, Namura S, Moskowitz MA, Bonventre JV. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. Proc Natl Acad Sci USA 1999, 96, 12866-12869 |
13 | Kim JC, Shin HC, Cha SW, Koh WS, Chung MK, Han SS. Evaluation of developmental toxicity in rats exposed to the environmental estrogen bisphenol A during pregnancy. Life Sci 2001, 69, 2611-2625 DOI ScienceOn |
14 | Linford NJ, Yang Y, Cook DG, Dorsa DM. Neuronal apoptosis resulting from high doses of the isoflavone genistein: role for calcium and p42/44 mitogen-activated protein kinase. J Pharmacol Exp Ther 2001, 299, 67-75 |
15 |
Murasawa S, Mori Y, Nozawa Y, Masaki H, Maruyama K, Tsutsumi Y, Moriguchi Y, Shibasaki Y, Tanaka Y, Iwasaka T, Inada M, Matsubara H. Role of calciumsensitive tyrosine kinase Pyk2/CAK |
16 | Oka T, Adati N, Shinkai T, Sakuma K, Nishimura T, Kurose K. Bisphenol A induces apoptosis in central neural cells during early development of Xenopus laevis. Biochem Biophys Res Commun 2003, 312, 877-882 DOI ScienceOn |
17 | Purves T, Middlemas A, Agthong S, Jude EB, Boulton AJ, Fernyhough P, Tomlinson DR. A role for mitogenactivated protein kinases in the etiology of diabetic neuropathy. FASEB J 2001, 15, 2508-2514 DOI ScienceOn |
18 |
Shim GJ, Wang L, Andersson S, Nagy N, Kis LL, Zhang Q, Makela S, Warner M, Gustafsson JA. Disruption of the estrogen receptor |
19 |
Gomez-Santos C, Ferrer I, Reiriz J, Vinals F, Barrachina M, Ambrosio S. |
20 |
Seo SR, Chong SA, Lee SI, Sung JY, Ahn YS, Chung KC, Seo JT. |
21 | Sogawa N, Onodera K, Sogawa CA, Mukubo Y, Fukuoka H, Oda N, Furuta H. Bisphenol A enhances cadmium toxicity through estrogen receptor. Methods Find Exp Clin Pharmacol 2001, 23, 395-399 DOI ScienceOn |
22 | Papaconstantinou AD, Umbreit TH, Fisher BR, Goering PL, Lappas NT, Brown KM. Bisphenol A-induced increase in uterine weight and alterations in uterine morphology in ovariectomized B6C3F1 mice: role of the estrogen receptor. Toxicol Sci 2000, 56, 332-329 DOI ScienceOn |
23 | Raychoudhury SS, Flowers AF, Millette CF, Finlay MF. Toxic effects of polychlorinated biphenyls on cultured rat Sertoli cells. J Androl 2000, 21, 964-973 |
24 |
Barkhem T, Carlsson B, Nilsson Y, Enmark E, Gustafsson J, Nilsson S. Differential response of estrogen receptor |
25 | Brotons JA, Olea-Serrano MF, Villalobos M, Pedraza V, Olea N. Xenoestrogens released from lacquer coating in food cans. Environ Health Perspect 1995, 103, 608-612 DOI |
26 |
Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors |
27 |
Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, Piao JH, Yagita H, Okumura K, Doi T, Nakano H. NF- |
28 | Sugita-Konishi Y, Shimura S, Nishikawa T, Sunaga F, Naito H, Suzuki Y. Effect of Bisphenol A on non-specific immunodefenses against non-pathogenic Escherichia coli. Toxicol Lett 2003, 136, 217-227 |
29 |
Hrabovszky E, Steinhauser A, Barabas K, Shughrue PJ, Petersen SL, Merchenthaler I, Liposits Z. Estrogen receptor- |
30 | Nilsson S, Makela S, Treuter E, Tujague M, Thomsen J, Andersson G, Enmark E, Pettersson K, Warner M, Gustafsson JA. Mechanisms of estrogen action. Physiol Rev 2001, 81, 1535-1565 DOI |
31 | Kuppers E, Ivanova T, Karolczak M, Lazarov N, Fohr K, Beyer C. Classical and nonclassical estrogen action in the developing midbrain. Horm Behav 2001, 40, 196-202 DOI ScienceOn |
32 |
Jung KM, Park KS, Oh JH, Jung SY, Yang KH, Song YS, Son DJ, Park YH, Yun YP, Lee MK, Oh KW, Hong JT. Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy- |
33 | Lee YM, Lee SM, Son DJ, Lee SY, Park HJ, Nam SY, Kim DJ, Yun YW, Yoo HS, Oh KW, Kim TS, Han YS. Bisphenol a disturbs intracellular calcium homeostasis and its relationship with cytotoxicity. J Toxicol Public Health 2004, 20, 57-66 |
34 |
Paris F, Balaguer P, Terouanne B, Servant N, Lacoste C, Cravedi JP, Nicolas JC, Sultan C. Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit |
35 | Couse JF, Korach KS. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 1999, 20, 358-417 DOI ScienceOn |
36 |
Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. The NF- |
37 | Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72, 248-254 DOI ScienceOn |
38 |
Takayanagi S, Tokunaga T, Liu X, Okada H, Matsushima A, Shimohigashi Y. Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor |
39 | Moore SA, Huang N, Hinthong O, Andres RD, Grammatopoulos TN, Weyhenmeyer JA. Human angiotensin II type-2 receptor inhibition of insulin-mediated ERK-2 activity via a G-protein coupled signaling pathway. Brain Res Mol Brain Res 2004, 124, 62-69 DOI ScienceOn |
40 |
Coleman KM, Dutertre M, El-Gharbawy A, Rowan BG, Weigel NL, Smith CL. Mechanistic differences in the activation of estrogen receptor- |
41 | Takao T, Nanamiya W, Nagano I, Asaba K, Kawabata K, Hashimoto K. Exposure with the environmental estrogen bisphenol A disrupts the male reproductive tract in young mice. Life Sci 1999, 65, 2351-2357 DOI ScienceOn |
42 | Washington W, Hubert L, Jones D, Gray WG. Bisphenol a binds to the low-affinity estrogen binding site. In Vitr Mol Toxicol 2001, 14, 43-51 DOI ScienceOn |
43 |
Jiang B, Xu S, Hou X, Pimentel DR, Brecher P, Cohen RA. Temporal control of NF- |
44 | Oh JH, Jung HK, Park YJ, Kim CK, Chung SY, Park NG, Yun YW, Kim DJ, Ha TY, Song YS, Lee YM, Oh K, Hong JT. Inhibitory effects of ochratoxin A on nerve growth factor-induced neurite extension through downregulation of p38 MAP kinase and AP-1 activation in cultured pheochromocytoma cells. J Toxicol Environ Health A 2004, 67, 357-371 DOI ScienceOn |
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