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http://dx.doi.org/10.4142/jvs.2007.8.1.1

Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil  

Obidike, I. Reginald (Department of Veterinary Physiology and Pharmacology, University of Nigeria)
Maduabuchi, Igwebuike U. (Department of Veterinary Anatomy, University of Nigeria)
Olumuyiwa, Shoyinka S.V. (Department of Veterinary Pathology and Microbiology, University of Nigeria)
Publication Information
Journal of Veterinary Science / v.8, no.1, 2007 , pp. 1-5 More about this Journal
Abstract
Potential negative effects of exposure to Nigerian Qua Iboe Brent crude oil on the reproductive system of male rats was investigated. Forty Sprague-Dawley rats were used for the experiment. Exposure to Nigerian Qua Iboe Brent crude oil was achieved via oral administration of increasing doses (0.1, 0.2, and 0.4 ml/rat) every other day for 4 weeks. Cauda epididymal sperm reserves and relative weights of the testes as well as histological features of the testes of rats that received the crude oil treatment were compared to those of control rats. The results described here showed a significant (p < 0.01) dosedependent reduction in the cauda epididymal sperm reserves of rats that received crude oil treatment relative to the control group. The morphology of testes of the crude oil-exposed rats was characterized by the presence of interstitial exudates, degeneration, and necrosis of spermatogenic and interstitial (Leydig) cells. Findings indicate that exposure of male rats to Nigerian Qua Iboe Brent crude oil may have adversely affected their reproductive systems. This may imply possible reproductive health hazards for animals and humans that may be exposed to this environmental pollutant, especially in areas where oil spillage is a common feature.
Keywords
cauda epididymal sperm reserve; crude oil; rat; seminiferous tubule; testes;
Citations & Related Records

Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 6
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