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http://dx.doi.org/10.3348/kjr.2016.17.5.758

Hepatic Involvement of Histiocytic Sarcoma: CT and MRI Findings  

Kubo, Takatoshi (Department of Radiology, Graduate School of Medicine, University of Tokyo)
Kiryu, Shigeru (Department of Radiology, Institute of Medical Science, University of Tokyo)
Akai, Hiroyuki (Department of Radiology, Institute of Medical Science, University of Tokyo)
Ota, Yasunori (Department of Pathology, Institute of Medical Science, University of Tokyo)
Tojo, Arinobu (Department of Hematology and Oncology, Institute of Medical Science, University of Tokyo)
Yoshida, Hideo (Department of Gastroenterology, Japanese Red Cross Medical Center)
Kato, Naoya (Department of Advanced Medical Science, Institute of Medical Science, University of Tokyo)
Nakano, Yoshiyasu (Department of Radiology, Institute of Medical Science, University of Tokyo)
Ohtomo, Kuni (Department of Radiology, Graduate School of Medicine, University of Tokyo)
Publication Information
Korean Journal of Radiology / v.17, no.5, 2016 , pp. 758-762 More about this Journal
Abstract
Histiocytic sarcoma in the liver is an extremely rare hematological malignancy. Herein, we reported the case of a 68-year-old woman who presented with characteristic wedge-shaped abnormality bounded by hepatic veins on computed tomography and magnetic resonance imaging of the liver. In the wedge-shaped area, decreased portal flow and the deposition of iron were observed. These imaging findings are consistent with intrasinusoidal tumor cell infiltration. A liver biopsy was performed, and histiocytic sarcoma was confirmed histopathologically.
Keywords
Histiocytic sarcoma; Magnetic resonance imaging; Computed tomography; Liver;
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1 Grogan TM, Pileri SA, Chan JKC, Weiss LM, Fletcher CDM. Histiocytic sarcoma. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri S, Stein H, et al., eds. World Health Organization classification of tumours pathology and genetics of tumours of haematopoietic and lymphoid tissues, 4th ed. Lyon: IARC Press, 2008:356-357
2 Hornick JL, Jaffe ES, Fletcher CD. Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy. Am J Surg Pathol 2004;28:1133-1144   DOI
3 Kimura H, Nasu K, Sakai C, Shiga Y, Miyamoto E, Shintaku M, et al. Histiocytic sarcoma of the spleen associated with hypoalbuminemia, hypo gamma-globulinemia and thrombocytopenia as a possibly unique clinical entity--report of three cases. Leuk Lymphoma 1998;31:217-224   DOI
4 Porter DW, Gupte GL, Brown RM, Spray C, English MW, deVille DeGoyet J, et al. Histiocytic sarcoma with interdigitating dendritic cell differentiation. J Pediatr Hematol Oncol 2004;26:827-830
5 Kobayashi S, Kimura F, Hama Y, Ogura K, Torikai H, Kobayashi A, et al. Histiocytic sarcoma of the spleen: case report of asymptomatic onset of thrombocytopenia and complex imaging features. Int J Hematol 2008;87:83-87   DOI
6 Audouin J, Vercelli-Retta J, Le Tourneau A, Adida C, Camilleri-Broet S, Molina T, et al. Primary histiocytic sarcoma of the spleen associated with erythrophagocytic histiocytosis. Pathol Res Pract 2003;199:107-112   DOI
7 Yamamoto S, Tsukamoto T, Kanazawa A, Shimizu S, Morimura K, Toyokawa T, et al. Laparoscopic splenectomy for histiocytic sarcoma of the spleen. World J Gastrointest Surg 2013;5:129-134   DOI
8 Oka K, Nakamine H, Maeda K, Yamakawa M, Imai H, Tada K, et al. Primary histiocytic sarcoma of the spleen associated with hemophagocytosis. Int J Hematol 2008;87:405-409   DOI
9 Shang SS, Furlan A, Almusa O, Ahmed-Amr HM, Bae KT. Regional presentation of hepatic diseases: CT and MR imaging findings of differential diagnosis. Acta Radiol 2010;51:832-841   DOI
10 Lupescu IG, Grasu M, Capsa R, Pitrop A, Georgescu SA. Hepatic perfusion disorders: computer-tomographic and magnetic resonance imaging. J Gastrointestin Liver Dis 2006;15:273-279
11 Bayraktar UD, Seren S, Bayraktar Y. Hepatic venous outflow obstruction: three similar syndromes. World J Gastroenterol 2007;13:1912-1927   DOI
12 Westphalen AC, Qayyum A, Yeh BM, Merriman RB, Lee JA, Lamba A, et al. Liver fat: effect of hepatic iron deposition on evaluation with opposed-phase MR imaging. Radiology 2007;242:450-455   DOI
13 Kadoya M, Matsui O, Kitagawa K, Kawamori Y, Yoshikawa J, Gabata T, et al. Segmental iron deposition in the liver due to decreased intrahepatic portal perfusion: findings at MR imaging. Radiology 1994;193:671-676   DOI