Browse > Article
http://dx.doi.org/10.3348/kjr.2013.14.3.470

Spinal Meningeal Melanocytoma with Benign Histology Showing Leptomeningeal Spread: Case Report  

Kim, Ok Hwa (Department of Radiology, Inje University Haeundae Paik Hospital)
Kim, Seon Jeong (Department of Radiology, Inje University Haeundae Paik Hospital)
Choo, Hye Jung (Department of Radiology, Inje University Busan Paik Hospital)
Lee, Sun Joo (Department of Radiology, Inje University Busan Paik Hospital)
Lee, In Sook (Department of Radiology, Busan National University Hospital)
Kim, Ji Yeon (Department of Pathology, Inje University Haeundae Paik Hospital)
Kim, Hoon (Department of Neurosurgery, Inje University Haeundae Paik Hospital)
Publication Information
Korean Journal of Radiology / v.14, no.3, 2013 , pp. 470-476 More about this Journal
Abstract
Meningeal melanocytoma is a rare benign tumor with relatively good prognosis. However, local aggressive behavior of meningeal melanocytoma has been reported, especially in cases of incomplete surgical resection. Malignant transformation was raised as possible cause by prior reports to explain this phenomenon. We present an unusual case of meningeal melanocytoma associated with histologically benign leptomeningeal spread and its subsequent aggressive clinical course, and describe its radiological findings.
Keywords
Spine; Magnetic resonance imaging; Meninges; Neoplasm; Melanocytoma;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Painter, TJ, Chaljub, G, Sethi, R, Singh, H, Gelman, B,Intracranial and intraspinal meningeal melanocytosis, AJNR Am J Neuroradiol, 21, 1, 1349-1353(2000)
2 Roser, F, Nakamura, M, Brandis, A, Hans, V, Vorkapic, P, Samii, M,Transition from meningeal melanocytoma to primary cerebral melanoma. Case report, J Neurosurg, 101, 2, 528-531(2004)   DOI
3 Wang, F, Li, X, Chen, L, Pu, X,Malignant transformation of spinal meningeal melanocytoma. Case report and review of the literature, J Neurosurg Spine, 6, 3, 451-454(2007)   DOI
4 Uozumi, Y, Kawano, T, Kawaguchi, T, Kaneko, Y, Ooasa, T, Ogasawara, S,Malignant transformation of meningeal melanocytoma: a case report, Brain Tumor Pathol, 20, 4, 21-25(2003)   DOI
5 Bydon, A, Gutierrez, JA, Mahmood, A,Meningeal melanocytoma: an aggressive course for a benign tumor, J Neurooncol, 64, 5, 259-263(2003)   DOI
6 Limas C, Tio FO. Meningeal melanocytoma ("melanotic meningioma"). Its melanocytic origin as revealed by electron microscopy. Cancer 1972;30:1286-1294   DOI
7 Chacko, G, Rajshekhar, V,Thoracic intramedullary melanocytoma with long-term follow-up, J Neurosurg Spine, 9, 7, 589-592(2008)   DOI
8 Chen, CJ, Hsu, YI, Ho, YS, Hsu, YH, Wang, LJ, Wong, YC,Intracranial meningeal melanocytoma: CT and MRI, Neuroradiology, 39, 8, 811-814(1997)   DOI
9 Brat DJ. Melanocytic Neoplasm of Central Nerveous System. In: Perry A, Brat DJ, eds. Practical Surgical Neuropathology: A Diagnostic Approach. Philadelphia: Churchill Livingstone, 2010:353-359
10 Clarke, DB, Leblanc, R, Bertrand, G, Quartey, GR, Snipes, GJ,Meningeal melanocytoma. Report of a case and a historical comparison, J Neurosurg, 88, 10, 116-121(1998)   DOI