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http://dx.doi.org/10.3348/kjr.2013.14.3.439

The Role of Divided Injections of a Sclerotic Agent over Two Days in Balloon-Occluded Retrograde Transvenous Obliteration for Large Gastric Varices  

Yamagami, Takuji (Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine)
Yoshimatsu, Rika (Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine)
Miura, Hiroshi (Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine)
Matsumoto, Tomohiro (Department of Diagnostic Radiology, Japanese Red Cross Kyoto Daiichi Hospital)
Hasebe, Terumitsu (Department of Radiology, Tokai University Hachioji Hospital, Tokai University School of Medicine)
Publication Information
Korean Journal of Radiology / v.14, no.3, 2013 , pp. 439-445 More about this Journal
Abstract
Objective: To determine the safety and usefulness of a two-tiered approach to balloon-occluded retrograde transvenous obliteration (B-RTO) as a treatment for large gastric varices after portal hypertension. Materials and Methods: 50 patients were studied who underwent B-RTO for gastric varices between October 2004 and October 2011 in our institution. The B-RTO procedure was performed from the right femoral vein and the B-RTO catheter was retained until the following morning. Distribution of sclerotic agents in the gastric varices on fluoroscopy was evaluated in all patients on days 1 and 2. When distribution of sclerotic agents in the gastric varices on day 1 had been none or very scanty even though the volume of the sclerotic agent infused was above the acceptable level, a second infusion was administered on day 2. When distribution was satisfactory, the B-RTO catheter was removed. Results: In 8 (16%) patients, little or no sclerotic agent infused on day 1 was distributed in the gastric varices. However, on day 2, sclerotic agents were distributed in all gastric varices. Mean volume of ethanolamine oleate-iopamidol infused on day 1 was 24.6 mL and was 19.4 mL on day 2. Gastric varices were well obliterated with no recurrence. Complications caused by the sclerotic agent such as pulmonary edema or renal insufficiencies were not seen. Conclusion: When gastric varices are very large, a strategy involving thrombosis of only the drainage vein on the first day followed by infusing the sclerotic agent on the following day might be effective and feasible.
Keywords
Portal veins; Stomach, varices; Therapeutic blockade;
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