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http://dx.doi.org/10.3348/kjr.2013.14.2.343

F-18 Fluorodeoxyglucose PET/CT and Post Hoc PET/MRI in a Case of Primary Meningeal Melanomatosis  

Lee, Hong Je (Department of Nuclear Medicine, Dongnam Institute of Radiological & Medical Sciences (DIRAMS))
Ahn, Byeong-Cheol (Department of Nuclear Medicine, Kyungpook National University School of Medicine, Kyungpook National University Hospital)
Hwang, Seong Wook (Department of Pathology, Kyungpook National University School of Medicine, Kyungpook National University Hospital)
Cho, Suk Kyong (Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Kim, Hae Won (Department of Nuclear Medicine, Kyungpook National University School of Medicine, Kyungpook National University Hospital)
Lee, Sang-Woo (Department of Nuclear Medicine, Kyungpook National University School of Medicine, Kyungpook National University Hospital)
Hwang, Jeong-Hyun (Department of Neurosurgery, Kyungpook National University School of Medicine, Kyungpook National University Hospital)
Lee, Jaetae (Department of Nuclear Medicine, Kyungpook National University School of Medicine, Kyungpook National University Hospital)
Publication Information
Korean Journal of Radiology / v.14, no.2, 2013 , pp. 343-349 More about this Journal
Abstract
Primary meningeal melanomatosis is a rare, aggressive variant of primary malignant melanoma of the central nervous system, which arises from melanocytes within the leptomeninges and carries a poor prognosis. We report a case of primary meningeal melanomatosis in a 17-year-old man, which was diagnosed with $^{18}F$-fluorodeoxyglucose (F-18 FDG) PET/CT, and post hoc F-18 FDG PET/MRI fusion images. Whole-body F-18 FDG PET/CT was helpful in ruling out the extracranial origin of melanoma lesions, and in assessing the therapeutic response. Post hoc PET/MRI fusion images facilitated the correlation between PET and MRI images and demonstrated the hypermetabolic lesions more accurately than the unenhanced PET/CT images. Whole body F-18 FDG PET/CT and post hoc PET/MRI images might help clinicians determine the best therapeutic strategy for patients with primary meningeal melanomatosis.
Keywords
Meningeal melanomatosis; F-18 FDG; PET/CT; post hoc PET/MRI;
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