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http://dx.doi.org/10.3348/kjr.2012.13.5.530

Partially Cystic Thyroid Nodules: Ultrasound Findings of Malignancy  

Park, Jang Mi (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
Choi, Yoonjung (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
Kwag, Hyon Joo (Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
Publication Information
Korean Journal of Radiology / v.13, no.5, 2012 , pp. 530-535 More about this Journal
Abstract
Objective: To seek for the ultrasound (US) findings of partially cystic thyroid nodules that are associated with malignancy. Materials and Methods: We reviewed the US characteristics of 22 surgically confirmed partially cystic papillary carcinomas, and compared them with those of 80 benign partially cystic nodules. The review cases were selected in a random order from a total of 1029 partially cystic nodules that were diagnosed with an US-guided fine needle aspiration biopsy over a period of 8 years (June 2003 to October 2010) at our institution. Results: In partially cystic thyroid nodules, a taller-than-wide shape (100%, p < 0.001) and spiculated or microlobulated margin (58.3%, p = 0.003) were significantly associated with malignancy. In terms of internal solid portion of the nodule, eccentric configuration (68.0%, p < 0.001), non-smooth margin (81.3%, p < 0.001), hypoechogenecity (30.0%, p < 0.042), and microcalcification (89.5%, p < 0.001) were more frequently demonstrated in malignant nodules than benign ones. Conclusion: In partially cystic thyroid nodules, understanding the characteristics of US findings is important to make a precise diagnosis of malignant nodules.
Keywords
Partially cystic nodule; Partially cystic papillary carcinoma; Cystic papillary carcinoma; Thyroid Nodule; Ultrasound;
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