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http://dx.doi.org/10.3348/kjr.2012.13.2.249

Micropapillary Lung Cancer with Breast Metastasis Simulating Primary Breast Cancer due to Architectural Distortion on Images  

Ko, Kyung-Ran (Department of Diagnostic Radiology, Center for Breast Cancer, National Cancer Center)
Ro, Jae-Yoon (Department of Pathology, Center for Breast Cancer, National Cancer Center)
Hong, Eun-Kyung (Department of Pathology, Center for Breast Cancer, National Cancer Center)
Lee, See-Yeon (Department of Surgery, Center for Breast Cancer, National Cancer Center)
Publication Information
Korean Journal of Radiology / v.13, no.2, 2012 , pp. 249-253 More about this Journal
Abstract
A 47-year-old Korean woman with right middle lobe lung adenocarcinoma, malignant pleural effusion, and multiple lymph node and bone metastases, after three months of lung cancer diagnosis, presented with a palpable right breast mass. Images of the right breast demonstrated architectural distortion that strongly suggested primary breast cancer. Breast biopsy revealed metastatic lung cancer with a negative result for estrogen receptor (ER), progesterone receptor (PR) and mammaglobin, and a positive result for thyroid transcription factor-1 (TTF-1). We present a case of breast metastasis from a case of lung cancer with an extensive micropapillary component, which was initially misinterpreted as a primary breast cancer due to unusual image findings with architectural distortion.
Keywords
Metastasis; Breast images; Lung cancer; Micropapillary carcinoma;
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