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http://dx.doi.org/10.3348/kjr.2011.12.6.651

Diffusion Tensor Imaging: Exploring the Motor Networks and Clinical Applications  

Ahn, Sung-Soo (Department of Radiology, Yonsei University College of Medicine)
Lee, Seung-Koo (Department of Radiology, Yonsei University College of Medicine)
Publication Information
Korean Journal of Radiology / v.12, no.6, 2011 , pp. 651-661 More about this Journal
Abstract
With the advances in diffusion magnetic resonance (MR) imaging techniques, diffusion tensor imaging (DTI) has been applied to a number of neurological conditions because DTI can demonstrate microstructures of the brain that are not assessable with conventional MR imaging. Tractography based on DTI offers gross visualization of the white matter fiber architecture in the human brain in vivo. Degradation of restrictive barriers and disruption of the cytoarchitecture result in changes in the diffusion of water molecules in various pathological conditions, and these conditions can also be assessed with DTI. Yet many factors may influence the ability to apply DTI clinically, so these techniques have to be used with a cautious hand.
Keywords
Diffusion tensor imaging; Tractography; Diffusion weighted imaging;
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1 Carano RA, Li F, Irie K, Helmer KG, Silva MD, Fisher M, et al. Multispectral analysis of the temporal evolution of cerebral ischemia in the rat brain. J Magn Reson Imaging 2000;12:842-858   DOI   ScienceOn
2 Nelles M, Gieseke J, Flacke S, Lachenmayer L, Schild HH, Urbach H. Diffusion tensor pyramidal tractography in patients with anterior choroidal artery infarcts. AJNR Am J Neuroradiol 2008;29:488-493   DOI   ScienceOn
3 Hosomi A, Nagakane Y, Yamada K, Kuriyama N, Mizuno T, Nishimura T, et al. Assessment of arcuate fasciculus with diffusion-tensor tractography may predict the prognosis of aphasia in patients with left middle cerebral artery infarcts. Neuroradiology 2009;51:549-555   DOI   ScienceOn
4 McKinstry RC, Mathur A, Miller JH, Ozcan A, Snyder AZ, Schefft GL, et al. Radial organization of developing preterm human cerebral cortex revealed by non-invasive water diffusion anisotropy MRI. Cereb Cortex 2002;12:1237-1243   DOI   ScienceOn
5 Eriksson SH, Symms MR, Rugg-Gunn FJ, Boulby PA, Wheeler-Kingshott CA, Barker GJ, et al. Exploring white matter tracts in band heterotopia using diffusion tractography. Ann Neurol 2002;52:327-334   DOI   ScienceOn
6 Hoon AH Jr, Lawrie WT Jr, Melhem ER, Reinhardt EM, Van Zijl PC, Solaiyappan M, et al. Diffusion tensor imaging of periventricular leukomalacia shows affected sensory cortex white matter pathways. Neurology 2002;59:752-756   DOI   ScienceOn
7 Kapeller P, Schmidt R, Fazekas F. Qualitative MRI: evidence of usual aging in the brain. Top Magn Reson Imaging 2004;15:343-347   DOI   ScienceOn
8 Salat DH, Tuch DS, Greve DN, van der Kouwe AJ, Hevelone ND, Zaleta AK, et al. Age-related alterations in white matter microstructure measured by diffusion tensor imaging. Neurobiol Aging 2005;26:1215-1227   DOI   ScienceOn
9 Charlton RA, Barrick TR, McIntyre DJ, Shen Y, O'Sullivan M, Howe FA, et al. White matter damage on diffusion tensor imaging correlates with age-related cognitive decline. Neurology 2006;66:217-222   DOI   ScienceOn
10 Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, et al. White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study. Neurobiol Aging 2006;27:663-672   DOI   ScienceOn
11 Taoka T, Iwasaki S, Sakamoto M, Nakagawa H, Fukusumi A, Myochin K, et al. Diffusion anisotropy and diffusivity of white matter tracts within the temporal stem in Alzheimer disease: evaluation of the "tract of interest" by diffusion tensor tractography. AJNR Am J Neuroradiol 2006;27:1040-1045
12 Matsuo K, Mizuno T, Yamada K, Akazawa K, Kasai T, Kondo M, et al. Cerebral white matter damage in frontotemporal dementia assessed by diffusion tensor tractography. Neuroradiology 2008;50:605-611   DOI   ScienceOn
13 Ganguli M, Dodge HH, Shen C, DeKosky ST. Mild cognitive impairment, amnestic type: an epidemiologic study. Neurology 2004;63:115-121   DOI
14 Vaillancourt DE, Spraker MB, Prodoehl J, Abraham I, Corcos DM, Zhou XJ, et al. High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease. Neurology 2009;72:1378-1384   DOI   ScienceOn
15 Kubicki M, McCarley R, Westin CF, Park HJ, Maier S, Kikinis R, et al. A review of diffusion tensor imaging studies in schizophrenia. J Psychiatr Res 2007;41:15-30   DOI   ScienceOn
16 Kyriakopoulos M, Bargiotas T, Barker GJ, Frangou S. Diffusion tensor imaging in schizophrenia. Eur Psychiatry 2008;23:255-273   DOI   ScienceOn
17 Kanaan RA, Kim JS, Kaufmann WE, Pearlson GD, Barker GJ, McGuire PK. Diffusion tensor imaging in schizophrenia. Biol Psychiatry 2005;58:921-929   DOI   ScienceOn
18 Scollan DF, Holmes A, Winslow R, Forder J. Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging. Am J Physiol 1998;275:H2308-2318
19 Lin CP, Tseng WY, Cheng HC, Chen JH. Validation of diffusion tensor magnetic resonance axonal fiber imaging with registered manganese-enhanced optic tracts. Neuroimage 2001;14:1035-1047   DOI   ScienceOn
20 Okada T, Mikuni N, Miki Y, Kikuta K, Urayama S, Hanakawa T, et al. Corticospinal tract localization: integration of diffusiontensor tractography at 3-T MR imaging with intraoperative white matter stimulation mapping--preliminary results. Radiology 2006;240:849-857   DOI   ScienceOn
21 Hagmann P, Jonasson L, Maeder P, Thiran JP, Wedeen VJ, Meuli R. Understanding diffusion MR imaging techniques: from scalar diffusion-weighted imaging to diffusion tensor imaging and beyond. Radiographics 2006;26 Suppl 1:S205-223   DOI
22 Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 1986;161:401-407   DOI
23 Mori S, Oishi K, Faria AV. White matter atlases based on diffusion tensor imaging. Curr Opin Neurol 2009;22:362-369   DOI   ScienceOn
24 Berman J. Diffusion MR tractography as a tool for surgical planning. Magn Reson Imaging Clin N Am 2009;17:205-214   DOI   ScienceOn
25 Pizzini FB, Polonara G, Mascioli G, Beltramello A, Foroni R, Paggi A, et al. Diffusion tensor tracking of callosal fibers several years after callosotomy. Brain Res 2010;1312:10-17   DOI
26 Yang Q, Tress BM, Barber PA, Desmond PM, Darby DG, Gerraty RP, et al. Serial study of apparent diffusion coefficient and anisotropy in patients with acute stroke. Stroke 1999;30:2382-2390   DOI   ScienceOn
27 Chenevert TL, Brunberg JA, Pipe JG. Anisotropic diffusion in human white matter: demonstration with MR techniques in vivo. Radiology 1990;177:401-405   DOI
28 Lee SK, Kim DI, Kim J, Kim DJ, Kim HD, Kim DS, et al. Diffusion-tensor MR imaging and fiber tractography: a new method of describing aberrant fiber connections in developmental CNS anomalies. Radiographics 2005;25:53-65;discussion 66-58   DOI   ScienceOn
29 Zhang Y, Schuff N, Jahng GH, Bayne W, Mori S, Schad L, et al. Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease. Neurology 2007;68:13-19   DOI   ScienceOn
30 Kubicki M, Westin CF, Maier SE, Mamata H, Frumin M, Ersner-Hershfield H, et al. Diffusion tensor imaging and its application to neuropsychiatric disorders. Harv Rev Psychiatry 2002;10:324-336   DOI   ScienceOn
31 Pierpaoli C, Jezzard P, Basser PJ, Barnett A, Di Chiro G. Diffusion tensor MR imaging of the human brain. Radiology 1996;201:637-648   DOI
32 Jones DK, Horsfield MA, Simmons A. Optimal strategies for measuring diffusion in anisotropic systems by magnetic resonance imaging. Magn Reson Med 1999;42:515-525   DOI   ScienceOn
33 Papadakis NG, Xing D, Huang CL, Hall LD, Carpenter TA. A comparative study of acquisition schemes for diffusion tensor imaging using MRI. J Magn Reson 1999;137:67-82   DOI   ScienceOn
34 Hasan KM, Parker DL, Alexander AL. Comparison of gradient encoding schemes for diffusion-tensor MRI. J Magn Reson Imaging 2001;13:769-780   DOI   ScienceOn
35 Jones DK. The effect of gradient sampling schemes on measures derived from diffusion tensor MRI: a Monte Carlo study. Magn Reson Med 2004;51:807-815   DOI   ScienceOn
36 Turner R, Le Bihan D, Chesnick AS. Echo-planar imaging of diffusion and perfusion. Magn Reson Med 1991;19:247-253   DOI   ScienceOn
37 Anderson AW, Gore JC. Analysis and correction of motion artifacts in diffusion weighted imaging. Magn Reson Med 1994;32:379-387   DOI   ScienceOn
38 Yamada K, Kizu O, Mori S, Ito H, Nakamura H, Yuen S, et al. Brain fiber tracking with clinically feasible diffusion-tensor MR imaging: initial experience. Radiology 2003;227:295-301   DOI   ScienceOn
39 Ordidge RJ, Helpern JA, Qing ZX, Knight RA, Nagesh V. Correction of motional artifacts in diffusion-weighted MR images using navigator echoes. Magn Reson Imaging 1994;12:455-460   DOI   ScienceOn
40 Papadakis NG, Martin KM, Mustafa MH, Wilkinson ID, Griffiths PD, Huang CL, et al. Study of the effect of CSF suppression on white matter diffusion anisotropy mapping of healthy human brain. Magn Reson Med 2002;48:394-398   DOI   ScienceOn
41 Okada T, Miki Y, Fushimi Y, Hanakawa T, Kanagaki M, Yamamoto A, et al. Diffusion-tensor fiber tractography: intraindividual comparison of 3.0-T and 1.5-T MR imaging. Radiology 2006;238:668-678   DOI   ScienceOn
42 Nagae-Poetscher LM, Jiang H, Wakana S, Golay X, van Zijl PC, Mori S. High-resolution diffusion tensor imaging of the brain stem at 3 T. AJNR Am J Neuroradiol 2004;25:1325-1330
43 Le Bihan D, Mangin JF, Poupon C, Clark CA, Pappata S, Molko N, et al. Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 2001;13:534-546   DOI   ScienceOn
44 Douek P, Turner R, Pekar J, Patronas N, Le Bihan D. MR color mapping of myelin fiber orientation. J Comput Assist Tomogr 1991;15:923-929   DOI   ScienceOn
45 Mori S, Crain BJ, Chacko VP, van Zijl PC. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 1999;45:265-269   DOI   ScienceOn
46 Behrens TE, Woolrich MW, Jenkinson M, Johansen-Berg H, Nunes RG, Clare S, et al. Characterization and propagation of uncertainty in diffusion-weighted MR imaging. Magn Reson Med 2003;50:1077-1088   DOI   ScienceOn
47 Behrens TE, Berg HJ, Jbabdi S, Rushworth MF, Woolrich MW. Probabilistic diffusion tractography with multiple fibre orientations: What can we gain? Neuroimage 2007;34:144-155   DOI   ScienceOn
48 Oishi K, Zilles K, Amunts K, Faria A, Jiang H, Li X, et al. Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter. Neuroimage 2008;43:447-457   DOI   ScienceOn
49 Geyer S, Matelli M, Luppino G, Zilles K. Functional neuroanatomy of the primate isocortical motor system. Anat Embryol (Berl) 2000;202:443-474   DOI   ScienceOn
50 Lee JS, Han MK, Kim SH, Kwon OK, Kim JH. Fiber tracking by diffusion tensor imaging in corticospinal tract stroke: Topographical correlation with clinical symptoms. Neuroimage 2005;26:771-776   DOI   ScienceOn
51 Guye M, Parker GJ, Symms M, Boulby P, Wheeler-Kingshott CA, Salek-Haddadi A, et al. Combined functional MRI and tractography to demonstrate the connectivity of the human primary motor cortex in vivo. Neuroimage 2003;19:1349-1360   DOI   ScienceOn
52 Laundre BJ, Jellison BJ, Badie B, Alexander AL, Field AS. Diffusion tensor imaging of the corticospinal tract before and after mass resection as correlated with clinical motor findings: preliminary data. AJNR Am J Neuroradiol 2005;26:791-796
53 Lazar M, Alexander AL, Thottakara PJ, Badie B, Field AS. White matter reorganization after surgical resection of brain tumors and vascular malformations. AJNR Am J Neuroradiol 2006;27:1258-1271
54 Lu S, Ahn D, Johnson G, Cha S. Peritumoral diffusion tensor imaging of high-grade gliomas and metastatic brain tumors. AJNR Am J Neuroradiol 2003;24:937-941
55 Lu S, Ahn D, Johnson G, Law M, Zagzag D, Grossman RI. Diffusion-tensor MR imaging of intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltration index. Radiology 2004;232:221-228   DOI   ScienceOn
56 Powell HW, Parker GJ, Alexander DC, Symms MR, Boulby PA, Wheeler-Kingshott CA, et al. MR tractography predicts visual field defects following temporal lobe resection. Neurology 2005;65:596-599   DOI   ScienceOn
57 Jea A, Vachhrajani S, Widjaja E, Nilsson D, Raybaud C, Shroff M, et al. Corpus callosotomy in children and the disconnection syndromes: a review. Childs Nerv Syst 2008;24:685-692   DOI   ScienceOn
58 Klatzo I. Pathophysiological aspects of brain edema. Acta Neuropathol 1987;72:236-239   DOI   ScienceOn
59 Davis D, Ulatowski J, Eleff S, Izuta M, Mori S, Shungu D, et al. Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain. Magn Reson Med 1994;31:454-460   DOI   ScienceOn