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http://dx.doi.org/10.3348/kjr.2011.12.4.515

High Shear Stress at the Surface of Enhancing Plaque in the Systolic Phase is Related to the Symptom Presentation of Severe M1 Stenosis  

Suh, Dae-Chul (Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center)
Park, Sung-Tae (Department of Radiology, Soonchunhyang University Hospital)
Oh, Tack-Sun (Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center)
Park, Sang-Ok (Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center)
Lim, Ok-Kyun (Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center)
Park, Soon-Chan (Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center)
Ryu, Chang-Woo (Department of Radiology, East-West Neomedical Center, Kyunghee University, College of Medicine)
Lee, Deok-Hee (Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center)
Ko, Young-Bae (Department of Mechanical Engineering, Dankook University)
Lee, Sang-Wook (School of Mechanical and Automotive Engineering, University of Ulsan)
Yoon, Kyung-Hwan (Department of Mechanical Engineering, Dankook University)
Kim, Jong-Sung (Department of Neurology, University of Ulsan, College of Medicine, Asan Medical Center)
Publication Information
Korean Journal of Radiology / v.12, no.4, 2011 , pp. 515-518 More about this Journal
Abstract
The computational fluid dynamics methods for the limited flow rate and the small dimensions of an intracranial artery stenosis may help demonstrate the stroke mechanism in intracranial atherosclerosis. We have modeled the high wall shear stress (WSS) in a severe M1 stenosis. The high WSS in the systolic phase of the cardiac cycle was well-correlated with a thick fibrous cap atheroma with enhancement, as was determined using high-resolution plaque imaging techniques in a severe stenosis of the middle cerebral artery.
Keywords
Cerebral artery; Atherosclerosis; MRI, Plaque rupture, Fluid structure interaction;
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