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Synthesis of 5-Aminolevulinic Acid (ALA) and Its t-Butyl Ester for the Fluorescence Detection of Early Cancer  

Kang Min-Seok (College of Pharmacy, Kyung Hee University)
Kim Dong-Myung (College of Pharmacy, Kyung Hee University)
Kim Jeong Sook (PDT Bio Co. Ltd.)
Jeong Jin-Hyun (College of Pharmacy, Kyung Hee University)
Publication Information
Archives of Pharmacal Research / v.28, no.10, 2005 , pp. 1111-1113 More about this Journal
Abstract
5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminole-vulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.
Keywords
5-Aminolevulinic acid; Fluorescence detection; ALA; PDT;
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