Neuroprotective Effect of Wogonin: Potential Roles of Inflammatory Cytokines |
Piao, Hua-Zi
(Department of Pharmacology, College of Medicine, Ewha Institute of Neuroscience, Ewha Womens University, Department of pharmacology, College of Medicine, Yanbian University)
Jin, Shun-Ai (Yan-Ji Hospital) Chun, Hyang-Sook (Korea Food Research Institute) Lee, Jae-Chul (Department of Pharmacology, College of Medicine, Ewha Institute of Neuroscience, Ewha Womens University) Kim, Won-Ki (Department of Pharmacology, College of Medicine, Ewha Institute of Neuroscience, Ewha Womens University) |
1 | Chen, Y. C., Shen, S. C., Chen, L. G., Lee, T. J., and Yang L. L., Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide. Biachem Pharmacol., 61, 1417-1427 (2001) DOI PUBMED ScienceOn |
2 | Kim, W.-K., Seo, D. O., Choi, J.-J., and Ko, K.-H., Immunostimulated glial cells potentiate glucose deprivation-induced death of cultured rat cerebellar granule cells. J. Neurotrauma., 16, 415-424 (1999b) DOI PUBMED |
3 | Liu, B., Gao, H. M., Wang, J. Y., Jeohn, G. H., Cooper, C. L., and Hong, J. S., Role of nitric oxide in inflammation-mediated neurodegeneration. Ann. N. Y. Acad. Sci., 962, 318-331 (2002) DOI ScienceOn |
4 | Liu, B. and Hong, J. S., Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J. Pharmacol. Exp. Ther., 304,1-7 (2003) DOI ScienceOn |
5 | Park, B. K., Heo, M. Y., Park, H., and Kim, H. P., Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix. Eur. J. Pharmacol., 425, 153-157 (2001) DOI ScienceOn |
6 | Tsubuki, S., Saito, Y., Tomioka, M., Ito, H., and Kawashima, S., Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-Ieucine and tri-Ieucine. J. Biochem., 119, 572-576 (1996) DOI ScienceOn |
7 | Minami, M., Kuraishi, Y., Yabuuchi, K., Yamazaki, A., and Satoh, M., Induction of interleukine-1beta mRNA in rat brain after transient forebrain ischemia. J. Neurochem., 58, 390-392 (1992) DOI PUBMED |
8 | Wink, D. A., Kasprzak, K. S., Maragos, C. M., Elespuru, R. K., Misra, M., Dunams, T. M., Cebula, T. A., Koch, W. H., Andrews, A. W, and Allen, J. S., et al., DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science, 254, 1001-1003 (1991) DOI PUBMED |
9 | Yang, Y., Li, Q., Wang, C. X., Jeerakathil, T., and Shuaib, A., Dose-dependent neuroprotection with tiagabine in a focal cerebral ischemia model in rat. Neuroreport, 11, 2307-2311 (2000) DOI PUBMED ScienceOn |
10 | Lieb, K., Engels, S., and Fiebich, B. L., Inhibition of LPS-induced iNOS and NO synthesis in primary rat microglial cells. Neurochem Int., 42, 131-137 (2003) DOI ScienceOn |
11 | Kim, W.-K., Chung, J.-H., Kim, H.-C., and Ko, K. H., Nitric oxideenhanced excitotoxicity-independent apoptosis of glucosedeprived neurons. Neurasci. Res., 33, 281-289 (1999a) DOI ScienceOn |
12 | Kim, W.-K. and Ko, K. H., Potentiation of N-methyl-D-aspartatemediated neurotoxicity by immunostimulated murine microglia. J. Neurasci Res., 54,17-26 (1998) DOI ScienceOn |
13 | Drapier, J. C. and Hibbs, J. B. Jr., Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells. J. Immunol., 140, 2829-2838 (1988) |
14 | Kumar, S. M., Porterfield, D. M., Muller, K. J., Smith, P. J., and Sahley, C. L., Nerve injury induces a rapid efflux of nitric oxide (NO) detected with a novel NO microsensor. J. Neurosci., 21, 215-220 (2001) |
15 | Wakabayashi, I. and Yasui, K., Wogonin inhibits inducible prostaglandin E (2) production in macrophages. Eur. J. Pharmacol., 406, 477-481 (2000) DOI ScienceOn |
16 | Choi, J. J., Oh, Y. K., Kim, H. S., Kim, H. C., Ko, K. H., and Kim, W. K., Mimosine prevents the death of glucose-deprived immunostimulated astrocytes by scavenging peroxynitrite. Glia., 39, 37-46 (2002) DOI ScienceOn |
17 | Lauzurica, P, Martinez-Martinez, S., Marazuela, M., Gomez, del Arco P., Martinez, C., Sanchez-Madrid, F., and Redondo, J. M., Pyrrolidine dithiocarbamate protects mice from lethal shock induced by LPS or TNF-alpha. Eur. J. Immunol., 29, 1890-900 (1999) DOI ScienceOn |
18 | Polazzi, E., Gianni, T., and Contestabile, A., Microglial cells protect cerebellar granule neurons from apoptosis: evidence for reciprocal signaling. Glia, 36, 271-280 (2001) DOI ScienceOn |
19 | van der Bruggen, T., Nijenhuis, S., van Raaij, E., Verhoef, J., and van Asbeck. B. S., Lipopolysaccharide-induced tumor necrosis factor alpha production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway. Infect Immun., 67, 3824-3829 (1999) PUBMED |
20 | Chang, Y. L., Shen, J. J., Wung, B. S., Cheng, J. J., and Wang, D. L., Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. Mol. Pharmacol., 65, 507-513 (2001) |
21 | Kumar, S. M., Porterfield, D. M., Muller, K. J., Smith, P. J., and Sahley, C. L., Nerve injury induces a rapid efflux of nitric oxide (NO) detected with a novel NO microsensor. J. Neurosci., 21, 215-220 (2001) |
22 | Kim, W. G., Mohney, R. P., Wilson, B., Jeohn, G. H., Liu, B., and Hong, J. S., Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J. Neurosci., 20, 6309-6316 (2000) |
23 | Lee, J.-C., Cho, G.-S., Kim, H. J., and Kim, W.-K.., Augmented cerebral ischemic injury by activated macrophages/microglia: Role of nitric oxide. Glia, S2, 61 (2003) |
24 | Suk, K., Lee, H., Kang, S. S., Cho, G. J., and Choi, W. S., Flavonoid baicalein attenuates activation-induced cell death of brain microglia. J. Pharmacol. Exp. Ther., 305, 638-645 (2003) DOI ScienceOn |
25 | Nakamura, N., Hayasaka, S., Zhang, X. Y., Nagaki, Y., Matsumoto, M., Hayasaka, Y., and Terasawa, K., Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. Exp. Eye Res., 77, 195-202 (2003) DOI PUBMED ScienceOn |
26 | Kim, W.-K., Lee, J.-C., Cho, G.-S., Kim, H. J., Choi, and K., Choi, C., Time-dependent modulation of cerebral ischemic injury after lipopolysaccharide microinjection into rat corpus callosum. Glia, S2, 61 (2003) |
27 | Ma, W., Lim, W., Gee, K., Aucoin, S., Nandan, D., Kozlowski, M., Diaz-Mitoma, F., and Kumar, A., The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J. Biol. Chem., 276,13664-13674 (2001) DOI PUBMED |