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Synthesis of New Diselenide Compounds as Anti-Inflammatory Agents  

Shen, Liulan (College of Pharmacy, Kyung Hee University)
Shin, Kyung-Min (College of Pharmacy, Kyung Hee University)
Lee, Kyung-Tae (College of Pharmacy, Kyung Hee University)
Jeong, Jin-Hyun (College of Pharmacy, Kyung Hee University)
Publication Information
Archives of Pharmacal Research / v.27, no.8, 2004 , pp. 816-819 More about this Journal
Abstract
Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine induc-ers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphe-nyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as anti-inflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.
Keywords
Organoselenium compound; Bis-(hydroxyphenyl) diselenide; Diselenide; Anti-inflammatory activity;
Citations & Related Records

Times Cited By Web Of Science : 4  (Related Records In Web of Science)
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