Protective Effect of Fermented Red Ginseng on a Transient Focal Ischemic Rats |
Bae, Eun-Ah
(College of Pharmacy and Kyung Hee University)
Hyun, Yang-Jin (College of Pharmacy and Kyung Hee University) Choo, Min-Kyung (College of Pharmacy and Kyung Hee University) Oh, Jin-Kyung (College of Pharmacy and Kyung Hee University) Ryu, Jong-Hoon (College of Pharmacy and Kyung Hee University) Kim, Dong-Hyun (College of Pharmacy and Kyung Hee University) |
1 | Mochizuki, M., Yoo, C. Y., Matsuzawa, K., Sato, K., Saiki, I., Tono-oka, S., Samukawa, K., and Azuma, I., Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside , 20(R)- and 20(S)-ginsenoside , of Red ginseng. BioI. Pharm. Bull., 18, 1197-1202 (1995) |
2 | Park, E. K., Choo, M. K., Oh, J. K., Ryu, J. H., and Kim, D.-H., Ginsenoside reduces ischemic brain injury in rats. BioI. Pharm. Bull., 27, 433-436 (2004) DOI ScienceOn |
3 | Shibata, S., Fujita, M., Itokawa, H., Tanaka, O., and Ishii, T., Studies on the constituents of Japanese and Chinese crude druqs, XI. Panaxadiol, a sapogenin of ginseng roots. Chem. Pharm. Bull., 11,759-764 (1963) DOI PUBMED ScienceOn |
4 | Yuan, C. S., Attele, A. S., Wu, J. A., and Liu, D., Modulation of American ginseng on brainstem GABAergic effects in rats. J. Ethnopharmacol., 62, 215-222 (1998) DOI ScienceOn |
5 | Tanaka, N., Tanaka, O., and Shibata, S., Chemical studies on the oriental plant drugs. XXVIII. Saponins and sapogenins of ginseng; Stereochemistry of sapogenin of ginsenoside , and Rc. Chem. Pharm. Bull., 20, 1212-1216 (1972) DOI |
6 | Wakabayashi, C., Hasegawa, H., Murata, J., and Saiki, I., In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res., 9, 411-417 (1998) |
7 | Akao, T., Kanaoka, M., and Kobashi, K., Appearance of compound K, a major metbolite of ginsenoside , by intestinal bacteria, in rat plasma after oral administration-measurement of compound K by enzyme immunoassay. Biol. Pharm. Bull., 21, 245-249 (1998a) DOI PUBMED ScienceOn |
8 | Akao, T., Kida, H., Kanaoka, M., Hattori, M., and Kobashi, K., Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside , from Panax ginseng. J. Pharm. Pharmacol., 50, 1155-1160 (1998b) DOI ScienceOn |
9 | Bae, E. A., Han, M. J., Choo, M. K., Park, S. Y., and Kim, D.-H., Metabolism of 20(S)- and 20(R)-ginsenoside by human intestinal bacteria and its relation to in vitro biological activities. Biol. Pharm. Bull., 25, 58-63 (2002) DOI ScienceOn |
10 | Nagasawa, H. and Kogure, K., Correlation between cerebral blood flow nd histologic changes in a new rat model of middle cerebral artery occlusion. Stroke, 20, 1037-1043 (1989) DOI PUBMED ScienceOn |
11 | Kanaoka, M., Akao, T., and Kobashi, K., Metabolism of ginseng saponins, ginsenosides, by human intestinal bacteria. J. Tradit. Med., 11, 241-245 (1994) |
12 | Bae, E. A., Park, S. Y., and Kim, D.-H., Constitutive -glucosidases hydrolyzing ginsenoside , and from human intestinal bacteria. BioI. Pharm. Bull., 23, 1481-1485 (2000) DOI PUBMED ScienceOn |
13 | Sato, K., Mochizuki, M., Saiki, I., Yoo, Y. C., Samukawa, K., and Azuma, I., Inhibition of tumor angiogenesis and metastasis by a saponin of Panax ginseng-ginsenoside . BioI. Pharm. Bull., 17,635-639 (1994) DOI PUBMED ScienceOn |
14 | Wu, J. Y., Gardner, B. H., Murphy, C. I., Seals, J. R., Kensil, C. R., Recchia, J., Beltz, G. A., Newman, G. W., and Newman, M. J., Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine. J. Immunol., 148, 1519-1525 (1992) |
15 | Kitagawa, I., Yoshikawa, M., Yoshihara, M., Hayashi, T., and Taniyama, T., Chemical studies of crude drugs (1). Constituents of Ginseng radix rubra. Yakugaku Zasshi, 103, 612-622 (1983) DOI PUBMED |
16 | Kanaoka, M., Kato, H., Shimada, F., and Yano, S., Studies on the enzyme immunoassay of bioactive constituents contained in oriental medicinal drugs. VI. Enzyme immunoassay of ginesenoside , form Panax ginseng. Chem. Pharm. Bull., 40, 314-317 (1992) DOI PUBMED ScienceOn |
17 | Scardovi, V., 1984. Genus Bifidobacterium, p.1418-1434. In Krieg N. R., and J. G. Holt (ed.) Bergeys manual of systemic bacteriology. Williams and Wilkins, Baltimore |
18 | Barber, P. A., Demchuk, A. M., Hirt, L., and Buchan, A. M., Biochemistry of ischemic stroke. Adv. Neurol., 92, 151-164 (2003) PUBMED |
19 | Bartosik-Psujek, H., Belniak, E., and Stelmasiak, Z., Markers of inflammation in cerebral ischemia. Neurol. Sci., 24, 279-280 (2003) DOI ScienceOn |