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Quantitative Determination of Psoralen and Angelicin from Some Medicinal Herbs by High Performance Liquid Chromatography  

Dong, Nguyen-Thanh (College of Pharmacy, Chungnam National University)
Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
Kim, Young-Ho (College of Pharmacy, Chungnam National University)
Hwang, Gwi-Seo (College of Oriental Medicine, Kyungwon University)
Heo, Ok-Soon (Taejon Regional Food ＆ Drug Administration)
Kim, Se-Eun (Taejon Regional Food ＆ Drug Administratio)
Kang, Jong-Seong (College of Pharmacy, Chungnam National University)
Publication Information
Archives of Pharmacal Research / v.26, no.7, 2003 , pp. 516-520 More about this Journal
Abstract
A reversed-phase high performance liquid chromatographic method was developed to determine the contents of psoralen and angelicin from some medicinal herbs. The optimum eluent for chromatography was 20 v/v% acetonitrile in water on a Zorbax 300SB $C_{18}$ column. The identification was carried out by comparing the retention time and mass spectra of the relevant peaks with their standards. The variation of the concentration of psoralen and angelicin was wide between different species. The seeds of Psoralea corylifolia showed the highest contents of psoralen (7.8 mg/g) and angelicin (2.3 mg/g) among the tested herbs.
Keywords
Psoralen; Angelicin; Medicinal herb; HPLC;
Citations & Related Records

Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 4
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