Browse > Article

Antioxidative Constituents from Buddleia officinalis  

Piao, Mei-Shan (College of Pharmacy, Chosun University)
Kim, Mi-Ran (Research Center for Proteineous Materials, Chosun University)
Lee, Dong-Gun (School of Life Science and Biotechnology, Kyungpook National University)
Park, Yoonkyung (Research Center for Proteineous Materials, Chosun University)
Hahm, Kyung-Soo (Research Center for Proteineous Materials, Chosun University)
Moon, Young-Hee (College of Pharmacy, Chosun University)
Woo, Eun-Rhan (College of Pharmacy, Chosun University, Research Center for Proteineous Materials, Chosun University)
Publication Information
Archives of Pharmacal Research / v.26, no.6, 2003 , pp. 453-457 More about this Journal
Abstract
Four flavonoids (1-4), a phenylethyl glycoside (5), and a phenylpropanoid glycoside (6) were isolated from the flowers of Buddleia officinalis (Loganiaceae). Their structures were determined by chemical and spectral analysis. Among the isolated compounds, luteolin (1) and acteoside (6) exhibited the most potent antioxidative activity on the NBT superoxide scavenging assay. In addition, compounds 1-6 revealed weak antifungal activity, and no hemolytic activity.
Keywords
Buddleia officinalis; Antioxidant; NBT superoxide scavenging assay; Antifungal activity;
Citations & Related Records

Times Cited By Web Of Science : 13  (Related Records In Web of Science)
Times Cited By SCOPUS : 12
연도 인용수 순위
1 Blondle, S. E. and Houghten, R. A., Design of model amphipathic peptides having potent antimicrobial activities. Biochemistry, 31, 12688-12694 (1992)   DOI   ScienceOn
2 Ding, N., Yahara, S., and Nohara, T., Structure of mimengoside A, and B, new triterpenoid glycosides from Buddlejae Flos produced from China. Chem. Pharm. Bull., 40, 780-782 (1992)   DOI
3 Jahn, B., Martin, E., Stueben, A., and Bhakdi, S., Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay. J. Clin. Microbiol., 33, 661-667 (1995)   PUBMED
4 Matsuda H., Cai, H., Kubo M., Tosa H., and Inuma, M., Study on anti-cataract drugs from natural sources. II. Effects on Buddlejae Flos on in vitro aldose reductase activity. Biol. Pharm. Bull., 18, 462-466 (1995)
5 Pietta, P-G., Flavonoids as antioxidants. J. Nat. Prod., 63, 1035-1042 (2000)   DOI   PUBMED   ScienceOn
6 Pardo, F., Perich, F., Villarroel, L., and Torres R., Isolation of verbascoside, an antimicrobial constituents of Buddleja globosa leaves. J. Ethnopharmacol., 39, 221-222 (1993)   DOI   ScienceOn
7 Kim, H. J., Woo, E.-R., Shin, C.-G., Hwang, D. J., Park, H., and Lee, Y. S., HIV-1 integrase inhibitory phenylpropanoid glycosides from Clerodendron trichotomum. Arch. Pham. Res., 24, 286-291 (2001)   DOI   ScienceOn
8 Akdemir, Z. S., Tati, ii., Saraccoglu, i., ismailoglu, U. B., Sahin-Erdemli, i., and Calis, i., Polyphenolic compounds from Geranium pratense and their free radical scavenging activities. Phytochemistry, 56, 189-193 (2001)   DOI   ScienceOn
9 Houghton, P. J., Ethnopharmacology of some Buddleia species. J. Ethnopharmacol., 11, 293-308 (1984)   DOI   PUBMED   ScienceOn
10 Fan, W., Tezuka, Y., Komatsu, K., Namba, T., and Kadota, S., Prolyl endopeptidase inhibitors from the underground part of Rhodiola sacra S. H. Fu. Biol. Pharm. Bull., 22, 157-161 (1999)   DOI   PUBMED   ScienceOn
11 Houghton, P. J., Woldemariam, T. Z., Candau, M., Barnardo, A., Khen-Alafun, O., and Shangxiao, L., Buddlejone, a diterpene from Buddleja albiflora. Phytochemistry, 42, 485-488 (1996)   DOI   ScienceOn
12 Mensah, A. Y., Houghton, P. J., Bloomfield S., Vlietinck, A., and Berghe, D. V., Known and novel terpene from Buddleja globosa displaying selective antifungal activity against dermatophytes. J. Nat. Prod., 63, 1210-1213 (2000)   DOI   ScienceOn
13 Zimin, L. and Zhongjian, J., Phenylpropanoid and iridoid glycosides from Pedicularis strata. Phytochemistry, 30, 1341-1344 (1991)   DOI   ScienceOn
14 Kirby, A. J. and Schmidt, R. J., The antioxidant activity of Chinese herbs for eczema and of placebo herbs - I. J. Ethnopharmacol., 56, 103-108 (1997)   DOI   ScienceOn
15 Liao, Y.-H., Houghton, P. J., and Hoult, J. R. S., Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation. J. Nat. Prod., 62, 1241-1245 (1999)   DOI   ScienceOn
16 Fan, W., Tezuka, Y., Ni, K. M, and Kadota, S., Prolyl endopeptidase inhibitors from the underground part of Rhodiola sachalinensis. Chem. Pharm. Bull., 49, 396-401 (2001)   DOI   ScienceOn