Synthesis of 5-Chloro-3-[4-(3-diethylaminopropoxy)benzoyl]-2(4-methoxyphenyl)benzofuran as a Aggregation |
Choi, Hong-Dae
(Department of Chemistry, Dongeui University)
Seo, Pil-Ja (Department of Chemistry, Dongeui University) Son, Byeong-Wha (Department of Chemistry, Pukyong National University) Kang, Byoung-Won (Chemical Biology Institute) |
1 | Kim, Y. W., Lee, S. J., Seo, P. J., Choi, H. D., and Son, B. W., Synthesis of 2-alkylbenzofuran derivatives from substituted phenols using -(methylsulfinyl)ketones. J. Kor. Chem. Soc., 45, 377-381 (2001) |
2 | Corey, E. J. and Chaykovsky, M., Methylsulfinyl carbanion. Formation and applications to organic synthesis. J. Am. Chem. Soc., 87, 1345-1364 (1965) DOI |
3 | Kakizuka, A., Protein precipitation; a common etiology in neurodegenerative disorders. Trends Genet., 14, 396-402 (1998) DOI ScienceOn |
4 | Hercouet, A. and Le Corre, M., Une nouvelle voie d'acces aux benzofurannes. Tetrahedron Lett., 23, 2145-2148 (1979) |
5 | Hardy, J. and Allsop, D., Amyloid deposition as the central event in the aetiology Alzheimer's diesease. Trends Pharmacol. Sci., 12, 383-388 (1991) DOI ScienceOn |
6 | Howlett, D. R., Perry, A. E., Godfrey, F., Swatton, J. E., Jennings, K. H., Spitzfaden, C., Wadsworth, H., Wood, S. J., and Markwell, R. E., Inhibition of fibril formation in -amyloid peptide by a novel series of benzofurans. Biochem. J., 340, 283-289 (1999) DOI ScienceOn |
7 | Twyman, L. J. and Allsop, D., A short synthesis of the -amyloid (A) aggregation inhibitor. 3-p-Toluoyl-2-[4'-(3-diethylaminopropoxy) phenyl]benzofuran. Tetrahedron Lett., 40, 9383-9384 (1999) DOI ScienceOn |
8 | Choi, H. D. and Seo, P. J., Synthesis of 2-methylbenzofuran derivatives by means of Pummerer reaction of substituted phenols with -(methylsulfinyl)acetone. J. Kor. Chem. Soc., 45, 274-276 (2001) |