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Diterpenoids from the Stem Barks of Croton robustus  

Nattya-Ngamrojnavanich (Research Centre for Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University)
Sorasaree-Tonseiengsom (Research Centre for Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University)
Preecha-Lertpratchya (lnstitute of Biotechnology and Genetic Engineering, Chulalongkorn University)
Sophon-Roengsumran (lnstitute of Biotechnology and Genetic Engineering, Chulalongkorn University)
Songchan-Puthong (lnstitute of Biotechnology and Genetic Engineering, Chulalongkorn University)
Amorn, Petsom (lnstitute of Biotechnology and Genetic Engineering, Chulalongkorn University)
Publication Information
Archives of Pharmacal Research / v.26, no.11, 2003 , pp. 898-901 More about this Journal
Abstract
Three compounds were isolated from the stem barks of Croton robustus. Their structures were elucidated as trachyloban-19-oic, acid, trachyloban-19-ol and poilaneic acid by spectroscopic analysis. Among them, trachyloban-19-ol and methyl trachyloban-19-oate exhibited weak cytotoxic activity against gastric carcinoma and colon carcinoma with $ED_{50}$ of 9.2, 9.6 and 8.3, $9.1{\mu\textrm{g}}/mL$, respectively.
Keywords
Croton robustus; Trachyloban-19-oic acid; Trachyloban-19-ol; Poilaneic acid; Cytotoxic activity;
Citations & Related Records

Times Cited By Web Of Science : 3  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
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