1 |
Cresteil, T., Monsarrat, B., Alvinerie, P., Treluyer, J. M., Vieira, I. and Wright, M., Taxol metabolism by human liver microsomes: identifcation of cytochrome P450 isozymes involved in its biotramormation. Cancer. Res., 54, 386-392 (1994)
PUBMED
|
2 |
Kumar N., Taxol-induced polymerization of purified tubulin. Mechanism of action. J. Biol. Chem., 256, 10435-10441 (1991)
|
3 |
Nannan F'anday, V. R., Huizing, M. T., Willemse, Pax H. B., De Graeff, A., ten Bokkel Huinink, W. W., Vermorken, J. B. and Beijnier , J. H., Hepatic metabolism of paclitaxel and its impact in patients with altered hepatic function. Sem. Oncol., 24(supol 11), S11-34-S11-38 (1997)
|
4 |
Rahman, A., Korzekwa, K. R., Grogan, J., Gonzalezs, F. J. and Haris, J. W., Selective biotransformation of taxol to 6-hydroxytaxol by human cytochrome P450 2C8. Cancer Res., 54. 5543-5546 (1994)
PUBMED
|
5 |
Sparreboom, A., Van Asperen, J., Mayer, U., Schinkel, A. H., Smit, J. W., Meijer, D. K., Borst, P., Nooijen, W. J., Bejinen, J. H. and van Tellingen, O., Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by Pglycoprotein in the intestine. Proc. Natl. Acad. Sci. USA., 4, 2031-2035 (1997)
|
6 |
Walle, T., Walle, U. K., Kumar, G. N. and Bhalla, K. N., Taxol metabolism and disposition in cancer patients. Durg Metab. Disp., 23, 506-512 (1995)
|
7 |
Yamaoka, K., Tanigawara, Y., Nakagawa, T. and Uno, T., A pharmacokinetics analysis program for microcomputer. J. Pharm. Dyn., 4, 879-883 (1981)
DOI
|
8 |
Kumar G N., Walle, U. K. and Walle, T., Cytochrome P450 3A-mec iated human liver microsomal taxol 6-hydroxylation. J. Pharmacol. Exp. Ther., 268, 1160-1165 (1994)
PUBMED
|
9 |
Venook, A. P., Egorin, M. J., Rosner, G. L., Brown, T. D., Jahan, T. M., Batist, G., Hohl, R., Budman, D., Ratain, M. J., Kearns, C. M. and Schilsky, R. L., Phase and pharmacokinetic trial of paciltaxel in patients with hepatic dysfunction: cancer and leukemia group B 9264. J. Clin. Oncol., 16, 1811-1819 (1998)
DOI
PUBMED
|
10 |
Wiernik, P., Schwartz, E., Einzig, A., Strauman, J., Dutcher, J. P. and Lipton, R. B., Phasetrial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma. J. Clin. Oncol., 5, 1232-1239 (1987)
DOI
PUBMED
|
11 |
Sonnichsen, D. S., Hurwitz, C. A, Pratt, C. B., Shuster, J. J. and Reiling, M. V., Saturable pharmacokinetics and paclitaxel pharmacodynamics in child with solid tumors. J. Clin. Oncol., 12, 532-538 (1994)
DOI
PUBMED
|
12 |
Donel, M. G., Zucchetti, M., Munzone, E., Dlncalci, M. and Crosignani, A., Pharmacokinetics of anticancer agents in patients with impaired liver function. Eur. J. Cancer., 34, 33-46 (1998)
DOI
ScienceOn
|
13 |
Manfe di, J. J. and Horwitz, S. B., An antimitotic agent with a new mechanism of action. Pharmacol. Ther. 25, 83-125 (1984)
DOI
ScienceOn
|
14 |
Rowinsky, E., Eisenhauer, E., Chaudhry, V., Arbuck, S. G. and Donehower, R. C., Clinical toxicities encountered with paclitaxel (Taxol (R)). Sem. Oncol. 20 Suppl., 3, 1-15 (1993)
|
15 |
McGui e, W. P., Rowinsky, E. K., Rosenheim, N. B., Grumbine, F. C., Ettinger, D. S. and Armstrong, D. K., Taxol: A unique antineoplasic agent with significant activity in advanced ovariar epithelial neoplasm. Ann. Intern. Med., 111, 273-279 (1999)
|
16 |
Van den Berg, H. W., Desai, Z. R., Wilson, R., Kennedy, G., Bridges, J. M. and Shanks, R G., The pharmacokinetics of vincristine in man: reduced drug clearance associated with raised serum alkaline phosphatase and dose-limited elimination. Cancer Chemother. Pharmacol., 8, 215-219 (1982)
DOI
PUBMED
|
17 |
Brown, T., Havlin, K., Weiss, G., Cagnola, J., Koeller, J., Kuhn, J., Rizzo, J., Craig, J., Phillips, J. and Von Hoff, D., A Phasetrial of taxol given by a 6-hour intravenous infusion. J. Clin. Oncol., 9, 1261-1267 (1991)
DOI
PUBMED
|
18 |
Gianni L. Kearns, C., Giani, A., Capri, G., Vigano, L., Locatelli, A., Etonadonna, A. and Egorin, M., Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokineticl pha macodynarnic relationships in humans. J. Clin. Oncol., 13, 180-190 (1995)
DOI
PUBMED
|
19 |
Mase, H., Hiraoka, M., Suzuki, A and Nakanomyo, H., Determination of New anticancer drug, Paclitaxel, in biological fluids by high performance liquid chromatography. Yakugaku Zasshi, 114, 351-355 (1994)
DOI
PUBMED
|
20 |
Sarosy, G., Kohn, E., Stone, D. A., Rothenberg, M., Jacob, J., Adamo, D. O., Ognibene, F. P., Cunnion, R. E. and Reed, E., Phasestudy of taxol and granulocyte stimulating factor in patients with refractory ovarian cancer. J. Clin. Oncol. , 10, 1165-1170 (1992)
DOI
PUBMED
|
21 |
Brenner, D. E., Wiernik, P. H., Wesley, M. and Bachur, N. R., Acute doxorubicin toxicity: Relationship to pretreatment liver function, response, and pharmacokinetics in patients with acute nonlymphocytic leukemia. Cancer, 53, 1042-1048 (1984)
DOI
PUBMED
ScienceOn
|
22 |
Grem, J.L., Tutsch, K.D., Simon, K.J., Alberti, D.B., Willson, J., Tormiey, D., Swaminathan, S. and Trump ,D., Phasestudy of taxol administered as a short iv infusion daily for 5 days. Cancer. Treat. Rep., 71, 1179-1184 (1987)
PUBMED
|
23 |
Wiernik, P., Schwartz, E., Strauman, J., Dutcher, J. P., Lipton, R. B. and Paietta, E., Phaseclinical and pharmacokinetic study of taxol. Cancer Res., 47, 2486-2493 (1987)
PUBMED
|
24 |
Holmes, F. A., Walters, R. S., Theriault, R. L., Forman, A. D., Nevrton, L. K., Raber, M. N., Buzdar, A. U., Frye, D. K. and Hor obaqyi, G. N., Phase trial of taxol, an active drug in metastatic breast cancer. J. Natl. Cancer Inst., 83, 1797-1805 (1991)
PUBMED
|
25 |
Catalin, .J., Martin, N., Blachan, M. F. and Durand, A., Assay of paclitaxel (Taxol) in plasma and urine by high-performance liquid chromatography. J. Chromatogr. B Biomed. Sci., 709, 281-288 (1998)
DOI
ScienceOn
|
26 |
Sonnichsen, D. S., Liu Q, Schuetz. E, G., Schuetz, J. D., Pappo, A. and Reiling, M. V, Variability in human cytochrome P450 paclitaxel metabolism. J. Pharmacol. Exp. Ther., 275, 566-575 (1995)
PUBMED
|
27 |
Wani, M. C., Taylor, H. L., Wall, M.E., Coggon, P. and McPhail, A. T., Plant antitumor agnets. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Chem. Soc., 93, 2325-2327 (1971)
DOI
PUBMED
|
28 |
Hirosh, F., Masaaki, O., Ayuko, T., Hideshi, M. and Hiroyuki, K., Pha macokinetics of Paclitaxel in experimental animals part 2. Tissue distribution. JPN. J. Cancer Chemother., 21, 659-664 (1994)
|
29 |
Rowin sky E. K., Cazenave, L. A and Donehower, R.C., Taxol: A nove investigational antimicrotubule agent. J. Natl. Cancer Inst., 82, 1247-1259 (1990)
DOI
PUBMED
|