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Constituents of the Fruits and Leaves of Euodia daniellii  

Yoo, Sang-Woo (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kim, Ju-Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kang, Sam-Sik (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Son, Kun-Ho (Department of Food and Nutrition, Andong National University)
Chang, Hyeun-Wook (College of Pharmacy, Yeongnam University)
Kim, Hyun-Pyo (College of Pharmacy, Kangwon National University)
Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
Lee, Chong-Ock (Korea Research Institute of Chemical Toxicology)
Publication Information
Archives of Pharmacal Research / v.25, no.6, 2002 , pp. 824-830 More about this Journal
Abstract
Four flavonoid glycosides, flavaprin (7), evodioside B (8), vitexin (11), and hesperidin (12), as well as the coumarins bergapten (1), xanthotoxin (2), and isopimpinellin (3), the lignan simplexoside (10), the steroids ${\beta}-sitosterol$ (4) and daucosterol (5), the limonoids isolimonexic acid (6) and limonin (9), and uracil (13) and myo-inositol (14) have been isolated from Euodia daniellii. The structures of these compounds were established from spectral data. Among the isolates, bergapten showed cyclooxygenase-2 inhibitory activity with an $IC_{50}$ value of $6.2{\;}{\mu\textrm{g}}/ml. Flavonoids isolated from this plant exhibited no cytotoxic activity against the human tumor cell lines, A549, SKOV-3, SKMEL-2, XF498, and HCT15.
Keywords
Euodia daniellii; Rutaceae; Flavonoids; Coumarins; Steroids; Limonoids; Lignan; Nucleotide; Inositol; Cyclooxygenase-2;
Citations & Related Records

Times Cited By Web Of Science : 11  (Related Records In Web of Science)
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