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Free Radical Scavengers from the Heartwood of Juniperus chinensis  

Lim, Jong-Pil (College of Pharmacy, Woosuk University)
Song, Young-Cheol (College of Pharmacy, Woosuk University)
Kim, Jin-Wook (College of Pharmacy, Woosuk University)
Ku, Chung-Hwan (College of Pharmacy, Woosuk University)
Eun, Jae-Soon (College of Pharmacy, Woosuk University)
Leem, Kang-Hyun (College of Pharmacy, Woosuk University)
Kim, Dae-Keun (College of Pharmacy, Woosuk University)
Publication Information
Archives of Pharmacal Research / v.25, no.4, 2002 , pp. 449-452 More about this Journal
Abstract
The antioxidant activity of Juniperus chinensis (Cupressaceae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract of J. chinensis heartwood showed the strong antioxidant activity. The antioxidant activity of n-BuOH soluble fraction was stronger than that of the others, and the fraction was subjected to purification by repeated silica gel and Sephadex LH-20 column chromatography. Quercetin, naringenin, taxifolin, aromadendrin and isoquercitrin were isolated from the n-BuOH fraction. Their structures were elucidated by physico-chemical and spectroscopic studies.
Keywords
Juniperus chinensis; Antioxidant activity; Quercetin; Naringenin; Taxifolin; Aromadendrin; Isoquercitrin; DPPH radical;
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Times Cited By Web Of Science : 7  (Related Records In Web of Science)
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