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Design and Synthesis of Isoindoloquinoline Derivatives as Potential Antitumor Agents  

Lee, Heesoon (College of Pharmacy, Chungbuk National University)
Jeong, Ilyeong (College of Pharmacy, Chungbuk National University)
Yang, Sung-Il (College of Medicine, Kunkuk University)
Publication Information
Archives of Pharmacal Research / v.25, no.4, 2002 , pp. 416-420 More about this Journal
Abstract
A series of isoindoloquinoline derivatives was synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HCT15, SK-OV-3, MDA-MB-468 and T-47D).
Keywords
Antitumor agents; Isoindoloquinolinedione; Cytotoxic activity; Doxorubicin;
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