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Antioxidant Constituents from Setaria viridis  

Kwon, Yong-Soo (College of Pharmacy, Kangwon National University)
Kim, Eun-Young (College of Pharmacy, Kangwon National University)
Kim, Won-Jun (College of Pharmacy, Kangwon National University)
Kim, Woo-Kyung (College of Pharmacy, Kangwon National University)
Kim, Chang-Min (College of Pharmacy, Kangwon National University)
Publication Information
Archives of Pharmacal Research / v.25, no.3, 2002 , pp. 300-305 More about this Journal
Abstract
The EtOAc and n-BuOH soluble fractions from the aerial part of Setaria viridis showed a strong free radical scavenging activity. Six major compounds were isolated from these fractions. They were identified by spectral data as tricin (1), p-hydroxycinnamic acid (2), vitexin 2"-Ο-xyloside (3), orientin 2"-Ο-xyloside (4), $tricin-7-Ο-{\beta}-D-glucoside$ (5) and vitexin 2"-Ο-glucoside (6). Among these compounds, 4 and 5 exhibited strong free radical scavenging activities on 1, 1-diphenyl-2-picrylhydrazyl (DPPH). We further studied the effects of these isolated compounds on the lipid peroxidation in rat liver microsomes induced by non-enzymatic method. As expected, 4 and 5 exhibited significant inhibition on $ascorbic/Fe^{2-}$ induced lipid peroxidation in rat liver microsomes.ver microsomes.
Keywords
Setaria viridis; Flavonoids; Antioxidant; Free radical scavenging activity; DPPH (1,1-diphenyl-2-picrylhydrazyl) radical; Lipid peroxidation;
Citations & Related Records

Times Cited By Web Of Science : 7  (Related Records In Web of Science)
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