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Syntheses of ($\pm$)-Homoepibatidine Analogues  

Kim, Yong-Hyun (College of Pharmacy, SungKyunKwan University)
Oh, Chang-Young (College of Pharmacy, SungKyunKwan University)
Lee, Kee-Young (College of Pharmacy, SungKyunKwan University)
Lee, Yiu-Suk (College of Pharmacy, SungKyunKwan University)
Jung, Young-Hoon (College of Pharmacy, SungKyunKwan University)
Park, Hyun-Ju (College of Pharmacy, SungKyunKwan University)
Ham, Won-Hun (College of Pharmacy, SungKyunKwan University)
Publication Information
Archives of Pharmacal Research / v.25, no.1, 2002 , pp. 49-52 More about this Journal
Abstract
Syntheses of ($\pm$)-homoepibatidine analogues (2), which contain the 8-azabicyclo [3.2.1 ]octane ring system, were achieved by using palladium-catalyzed reductive-coupling reaction from 3 and the analgesic activity was tested by Mouse writhing antinociceptive assay
Keywords
Alkaloids; Homoepibatidine; Analgesics; Palladium; Stereocontrol;
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