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http://dx.doi.org/10.3839/jabc.2021.013

Antimicrobial activity of Caesalpinia sappan L. extract against skin flora  

Hwang, Mi Kyung (Department of Chemical Engineering, Chungwoon University)
Lee, Yong Hyun (Leadb Co., Ltd)
Kim, Dong Chung (Department of Chemical Engineering, Chungwoon University)
Publication Information
Journal of Applied Biological Chemistry / v.64, no.1, 2021 , pp. 83-87 More about this Journal
Abstract
Antimicrobial activity of an aqueous extract from Caesalpinia sappan L. was investigated against skin flora such as Escherichia coli, Staphylococcus aureus, Cutibacterium acnes, and Malassezia furfur. The yield and polyphenol content of the aqueous extract were 14.01±0.81% and 487.5±19.69 ㎍/mg-extract, respectively. The minimum inhibitory concentration of the aqueous extract against E. coli, S. aureus, C. acnes, and M. furfur was 0.875, 1.750, 1.750, and 1.750 mg/mL, respectively. In disc diffusion test, the aqueous extract of C. sappan L. increased the clear zone in a dose-dependent manner. The aqueous extract inhibited the microbial growth in a concentration-dependent manner.
Keywords
Antimicrobial activity; Aqueous extract; Caesalpinia sappan L.; Minimum inhibitory concentration; Skin flora;
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