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http://dx.doi.org/10.3839/jabc.2021.002

[Retracted] Inhibitory activity against biological enzyme and anti-microbial activity of phenolics from Sambucus sieboldiana var. pendula Leaves  

Lee, Eun-Ho (School of Food science & Biotechnology, Kyungpook National University)
Hong, Shin Hyub (School of Food science & Biotechnology, Kyungpook National University)
Park, Hye-Jin (School of Food science & Biotechnology, Kyungpook National University)
Kim, Byung-Oh (School of Food science & Biotechnology, Kyungpook National University)
Jung, Hee-Young (School of Applied Biosciences, Kyungpook National University)
Kang, In-Kyu (Department of Horticultural Science, Kyungpook National University)
Cho, Young-Je (School of Food science & Biotechnology, Kyungpook National University)
Publication Information
Journal of Applied Biological Chemistry / v.64, no.1, 2021 , pp. 5-11 More about this Journal
Abstract
The phenolics of Sambucus sieboldiana var. pendula leaves for functional resources were examined on inhibitory activity against biological enzyme and anti-microbial activity. The amount of phenolic compounds were 11.60±0.18 and 12.43±0.07 mg/g by water and 50% ethanol extraction, respectively. The antioxidative activity of phenolic in extracts was higher than solids. The inhibition activities on angiotensin converting enzyme were 92.08 and 78.33% at 200 ㎍/mL phenolic concentration in water and ethanol extracts, respectively. The xanthine oxidase inhibitory activity were 100% at 200 ㎍/mL phenolic in water and ethanol extracts, respectively. These result was higher than 70.37% of allopurinol as positive control at 200 ㎍/mL. The inhibitory activity against hyaluronidase were each 25.35 and 43.38% in water and ethanol extracts. The water extract from S. sieboldiana var. pendula leaves showed antibacterial activity on the Propionebacterium acnes, Staphylococcus aureus and Streptococcus mutans in water extract and S. mutans in ethanol extract. This result suggests that phenolic from S. sieboldiana var. pendula leaves are suitable as functional foods with anti-hypertension, anti-gout, anti-inflammation and anti-microorganism activities.
Keywords
Anti-gout; Anti-hypertension; Anti-inflammation; Anti-microorganism; Sambucus sieboldiana var. pendula;
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