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http://dx.doi.org/10.3839/jabc.2019.044

Phenolic compounds from the flowers of Coreopsis lanceolata  

Kim, Hyoung-Geun (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Oh, Hyun-Ji (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Ko, Jung-Hwan (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Jung, Young Sung (Department of Food Science and Biotechnology, Kyung Hee University)
Oh, Seon Min (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Lee, Yeong-Geun (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Kim, Dae-Ok (Department of Food Science and Biotechnology, Kyung Hee University)
Lee, Dae Young (Department of Herbal Crop Research, National Institute of Horticultural and Herbal Science, RDA)
Baek, Nam-In (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Publication Information
Journal of Applied Biological Chemistry / v.62, no.4, 2019 , pp. 323-326 More about this Journal
Abstract
The flowers of Coreopsis lanceolata were extracted with 80% aqueous MeOH and the concentrates were partitioned into EtOAc, n-BuOH, and H2O fractions. The repeated silica gel (SiO2) and octadecyl silica gel column chromatographies for the EtOAc fraction led to isolation of one flavonol and one benzoyl compounds. The chemical structures of the compounds were respectively determined as melanoxetin (1) and protocatechuic acid methyl ester (2) based on spectroscopic analyses including NMR, IR, and MS. These two compounds were isolated for the first time from C. lanceolata flowers in this study. All fractions and the isolated compounds were evaluated for 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical scavenging activities.
Keywords
Antioxidant; Benzoic acid; Coreopsis lanceolata; Flavonol; NMR;
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