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http://dx.doi.org/10.3839/jabc.2019.028

Aldose reductase inhibition of the methanolic extracts of selected noxious and exotic plants  

Lee, Ju Sung (Department of Plant Science and Technology, Chung-Ang University)
Woo, Dong Geon (Sejong Academy of Science and Arts)
Cho, Ga Eul (Sejong Academy of Science and Arts)
Lee, Sanghyun (Department of Plant Science and Technology, Chung-Ang University)
Publication Information
Journal of Applied Biological Chemistry / v.62, no.2, 2019 , pp. 203-209 More about this Journal
Abstract
The inhibition of aldose reductase (AR) by the extracts from sixteen noxious and exotic plants was examined. Among them, Aster pilosus showed the highest inhibition of AR ($IC_{50}$ value $0.11{\mu}g/mL$). This study showed that A. pilosus with promising AR-inhibitory activities can be utilized for the development of natural therapies for treating and managing diabetic complications.
Keywords
Aldose reductase; High-performance liquid chromatography; Noxious plant; Quercetin;
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