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http://dx.doi.org/10.3839/jabc.2019.021

Elicitor-treated extracts of Saururus chinensis inhibit the expression of inducible nitric oxide synthase and cyclooxygenase-2 enzyme expression in Raw cells for suppression of inflammation  

Lee, Eun-Ho (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University)
Park, Hye-Jin (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University)
Kim, Dong-Hee (National Development Institute of Korean Medicine)
Jung, Hee-Young (School of Applied Biosciences, Kyungpook National University)
Kang, In-Kyu (Department of Horticultural Science, Kyungpook National University)
Cho, Young-Je (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University)
Publication Information
Journal of Applied Biological Chemistry / v.62, no.2, 2019 , pp. 149-155 More about this Journal
Abstract
Elicitor treatment was performed to increase the anti-inflammatory activity of useful biological sources. The result showed that elicitor-treated Saururus chinensis leaf extracts positively affected nitric oxide (NO) production, and the expression of inducible NO synthase and cyclooxygenase-2 compared to extracts not exposed to elicitor treatment. This finding identified elicitor treatment as a suitable strategy for increasing the biological activity of S. chinensis. Therefore, elicitor-treated S. chinensis is useful both as health functional and medicinal materials.
Keywords
Cyclooxygenase-2; Elicitor; Inducible nitric oxide synthase; Nitric oxide; Saururus chinensis extracts;
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Times Cited By KSCI : 2  (Citation Analysis)
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