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http://dx.doi.org/10.3839/jabc.2019.019

Effect of Calendula arvensis extract on anti-melanogenesis and antimicrobial activity  

Kim, Hyun-Soo (Department of Food science and Technology, Jungwon University)
Publication Information
Journal of Applied Biological Chemistry / v.62, no.2, 2019 , pp. 137-141 More about this Journal
Abstract
At concentrations with little or no cytotoxicity, C. arvensis extract indicates the ability of high DPPH radical scavenging, inhibited tyrosinase activity, and decreased melanin content. The treatment of B16F10 cells with C. arvensis extract suppressed the protein expression of tyrosinase a dose-dependent manner. These results suggest that C. arvensis extract inhibits melanin synthesis by inhibiting tyrosinase expression and tyrosinase activity. In addition, C. arvensis extract showed antimicrobial activities against bacteria and yeast. These results indicate that C. arvensis extract may serve as nutraceutical and cosmeceutical agents.
Keywords
Antimicrobial activity; Calendula arvensis; Melanin; Tyrosinase;
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Times Cited By KSCI : 3  (Citation Analysis)
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