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http://dx.doi.org/10.3839/jabc.2017.035

In vitro anti-oxidant, anti-wrinkle and whitening effect of solvent fraction from takli-san  

Yu, Jae-Myo (National Development Institute of Korean Medicine)
Kang, Yun-Hwan (National Development Institute of Korean Medicine)
Kim, Dong-Hee (National Development Institute of Korean Medicine)
Park, Tae-Soon (National Development Institute of Korean Medicine)
Publication Information
Journal of Applied Biological Chemistry / v.60, no.3, 2017 , pp. 219-226 More about this Journal
Abstract
In this study, the activity of Takli-san for anti-oxidation, anti-wrinkle and whitening effect was verified and its applicability as a cosmetic material was confirmed. 1-1-diphenyl-2-picryl-hydrazyl radical scavenge, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenge, elastase and tyrosinase inhibitory activity were investigated by solvent fraction, and ethyl acetate fraction of water extract from Takli-san (TW-EA) showed the highest inhibitory activity. Western blot was performed to confirm anti-wrinkle and whitening effect in the cells, and it was investigeted that the TW-EA inhibition effect was superior to that of the positive contol used for the comparison test. Through the results of the experiments, the applicability as a cosmetic material of Takli-san was verified.
Keywords
Anti-oxidant; Anti-wrinkle; CCD-986sk; HEM; Takli-san; Whitening;
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Times Cited By KSCI : 13  (Citation Analysis)
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