[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.3839/jabc.2016.041

A novel nicotinoyl peptide, nicotinoyl-LVH, for collagen synthesis enhancement in skin cells

Kim, Hyoung Shik (Anti-Aging Research Institute of BIO-FD&C Co., Ltd.)
Ryu, Seung Hwan (Anti-Aging Research Institute of BIO-FD&C Co., Ltd.)
Kim, Hye In (Anti-Aging Research Institute of BIO-FD&C Co., Ltd.)
Cho, Seung Hee (Anti-Aging Research Institute of BIO-FD&C Co., Ltd.)
Lee, Jeong Hun (Anti-Aging Research Institute of BIO-FD&C Co., Ltd.)
Han, Byung Suk (AMI Cosmetic Co., Ltd.)
Lee, Kyung Rok (AMI Cosmetic Co., Ltd.)
Moh, Sang Hyun (Anti-Aging Research Institute of BIO-FD&C Co., Ltd.)

Publication Information

Journal of Applied Biological Chemistry / v.59, no.3, 2016 , pp. 239-242 More about this Journal

Abstract

A novel Nicotinoyl fused peptide, Nicotinoyl-LVH, was synthesized by solid phase peptide synthesis method, purified, and tested in cultured skin cells. Nicotinoyl-LVH enhanced the expression level of collagen mRNA and its fragments in fibroblasts. These data show that this novel Nicotinoyl peptide is a promising biomaterial in the anti-aging functional cosmetic market.

Keywords

Collagen synthesis; Cosmetic active ingredient; Nicotinoyl-LVH; Skin cell;

Citations & Related Records

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