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http://dx.doi.org/10.3839/jabc.2015.045

Inhibitory Effects of Soyasaponins on Antigen-induced Degranulation in RBL-2H3 Cells  

Yang, Seung Hwan (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Lee, Jung A (Bio-center, Gyeonggi Institute of Science and Technology Promotion)
Lee, Jae Yeon (Bio-center, Gyeonggi Institute of Science and Technology Promotion)
Ahn, Eun-Kyung (Bio-center, Gyeonggi Institute of Science and Technology Promotion)
Shin, Tai-Sun (Division of Food & Nutrition, Chonnam National University)
Tsukamoto, Chigen (Department of Applied Biological Chemistry, Iwate University)
Chung, Gyuhwa (Department of Biotechnology, Chonnam National University)
Suh, Joo-Won (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Publication Information
Journal of Applied Biological Chemistry / v.58, no.3, 2015 , pp. 287-290 More about this Journal
Abstract
Soyasaponins are glycosylated, which gives rise to a wide diversity of structures and functions. We evaluated for inhibitory effects of 4 soyasaponins on antigen-induced degranulation in RBL-2H3 Cells. 4 soyasaponins had shown dose-dependently inhibited histamine and ${\beta}$-hexosaminidase.
Keywords
allergic reaction; ${\beta}$-hexosaminidase; degranulation; RBL-2H3 Cells; soyasaponins;
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Times Cited By KSCI : 3  (Citation Analysis)
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