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http://dx.doi.org/10.3839/jabc.2015.009

Recovery Effect of Flavonoids from Morus alba Fruits on Alloxan-induced Pancreatic Islet in Zebrafish (Dinio rerio)  

Seo, Kyeong-Hwa (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Nam, Youn-Hee (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Kim, Young-Eon (Korea Food Research Institute)
Hong, Eock-Kee (School of Biotechnology and Bioengineering, Kangwon National University)
Hong, Bin-Na (Department of Audiology, Nambu University)
Kang, Tong-Ho (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Baek, Nam-In (Graduate School of Biotechnology and Department of Oriental Medicinal Biotechnology, Kyung Hee University)
Publication Information
Journal of Applied Biological Chemistry / v.58, no.1, 2015 , pp. 51-54 More about this Journal
Abstract
Flavonoids from Morus alba fruits were evaluated for recovery effect on the damage of alloxan-induced pancreatic islet in zebrafish. Alloxan treatment on the zebrafish embryo surely decreased the pancreatic islet size (p <0.001). Rutin, isoquercetin, and quercetin very significantly recovered the size (p <0.001) and the fluorescence intensity of pancreatic islet.
Keywords
alloxan; anti-diabetics; flavonoid; Morus alba; pancreatic islet; zebrafish;
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Times Cited By KSCI : 3  (Citation Analysis)
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