Browse > Article
http://dx.doi.org/10.3839/jabc.2014.028

Phytosterols from the Rice (Oryza sativa) Bran  

Jung, Ye-Jin (Graduate School of Biotechnology, Institute of Life Sciences & Resources, Kyung Hee University)
Park, Ji-Hae (Graduate School of Biotechnology, Institute of Life Sciences & Resources, Kyung Hee University)
Shrestha, Sabina (Graduate School of Biotechnology, Institute of Life Sciences & Resources, Kyung Hee University)
Song, Myoung-Chong (Intelligent Synthetic Biology Center, KAIST)
Cho, Suengmok (Korea Food Research Institute)
Lee, Chang-Ho (Korea Food Research Institute)
Han, Daeseok (Korea Food Research Institute)
Baek, Nam-In (Graduate School of Biotechnology, Institute of Life Sciences & Resources, Kyung Hee University)
Publication Information
Journal of Applied Biological Chemistry / v.57, no.2, 2014 , pp. 175-178 More about this Journal
Abstract
Three phytosterols of rare occurrence, schleicheol 2 (1), $7{\beta}$-hydroxysitosterol (2), and $7{\alpha}$-hydroxysitosterol (3), were isolated from the n-hexane fraction of rice (Oryza sativa) bran, for the first time. Some nuclear magnetic resonance (NMR) assignments in the literatures are inaccurate. This study employed two-dimensional NMR experiments to identify exact peak assignments.
Keywords
Oryza sativa L.; phytosterol; rice bran; schleicheol 2; $7{\alpha}$-hydroxysitosterol; $7{\beta}$-hydroxysitosterol;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Wilson TA, Ausman LM, Lawton CW, Hegsted DM, and Nicolosi RJ (2000) Comparative Cholesterol Lowering Properties of Vegetable Oils: Beyond Fatty Acids. J Am Coll Nutr 19, 601-7.   DOI
2 Zhang X, Geoffroy P, Miesch M, Julien-David D, Raul F, Aoude-Werner D et al. (2005) Gram-scale chromatographic purification of ${\beta}$-sitosterol synthesis and characterization of $\alpha$-sitosterol oxides. Steroids 70, 886-95.   DOI   ScienceOn
3 Berger A, Rein D, Schafer A, Monnard I, Gremaud G, Lambelet P et al. (2005) Similar cholesterol-lowering properties of rice bran oil, with varied ${\gamma}$-oryzanol, in mildly hypercholesterolemic men. Eur J Nutr 44, 163-73.   DOI   ScienceOn
4 Chang KC, Duh CY, Chen IS, and Tsai IL (2003) A cytotoxic butenolide, two new dolabellane diterpenoids, a chroman and a benzoquinol derivative Formosan Casearia membranacea. Planta Med 69, 667-72.   DOI   ScienceOn
5 Cui EJ, Park JH, Park HJ, Chung IS, Kim JY, Yeon SW et al. (2011) Isolation of sterols from cowpea (Vigna sinensis) seeds and their promotion activity on HO-1. J Korean Soc Appl Biol Chem 54, 362-6.   과학기술학회마을   DOI
6 Fang N, Yu S, and Badger TM (2003) Characterization of triterpene alcohol and sterol ferulates in rice bran using LC-MS/MS. J Agric Food Chem 51, 3260-7.   DOI   ScienceOn
7 Kim JS and Godber JS (2001) Oxidative stability and vitamin E levels increased in restructured beef roasts with added rice bran oil. J Food Qual 24, 17-26.   DOI   ScienceOn
8 McCaskill DR and Zhang F (1999) Use of rice bran oil in foods. Food Technol 53, 50-4.
9 Niu XM, Li SH, Peng LY, Lin ZW, Rao GX, and Sun HD (2001) Constituents from Limonia crenulata. J Asian Nat Prod Res 3, 299-311.   DOI   ScienceOn
10 Revilla E, Maria CS, Miramontes E, Bautista J, Garcia-Martinez A, Cremades O et al. (2009) Nutraceutical composition, antioxidant activity and hypocholesterolemic effect of a water-soluble enzymatic extract from rice bran. Food Res Int 42, 387-93.   DOI   ScienceOn
11 Rho EM, Jin Q, Jin HG, Shin JE, Choi EJ, Moon YH et al. (2010) Structural Implication in cytotoxic effects of sterols from Sellaginella tamariscina. Arch Pharm Res 33, 1347-53.   과학기술학회마을   DOI   ScienceOn
12 Roussi S, Winter A, Gosse F, Werner D, Zhang X, Marchioni E et al. (2005) Different apoptotic mechanisms are involved in the antiproliferative effects of $7{\beta}$-hydroxysitosterol and $7{\beta}$-hydroxycholesterol in human colon cancer cells. Cell Death Differ 12, 128-35.   DOI   ScienceOn
13 Santana O, Reina M, Fraga BM, Sanz J, and Gonzalez-Coloma A (2012) Antifeedant activity of fatty acid esters and phytosterols from Echium wildpretii. Chem Biodiv 9, 567-76.   DOI   ScienceOn
14 Tanaka A, Kato A, and Tsuchiya T (1971) Isolation of methyl ferulate from rice bran oil. J Am Oil Chem Soc 48, 95-7.   DOI
15 Lee DY, Lee SJ, Kwak HY, Jung LK, Heo J, Hong SY et al. (2009) Sterols isolated from Nuruk (Rhizopus oryzae KSD-815) inhibit the migration of cancer cells. J Microbiol Biotechnol 19, 1328-32.   과학기술학회마을   DOI   ScienceOn
16 Parrado J, Miramontes E, Jover M, Gutierrez JF, Collantes L de Teran, and Bautista J (2006) Preparation of a rice bran enzymatic extract with potential use as functional food. Food Chem 98, 742-8.   DOI   ScienceOn
17 Pettit GR, Numata A, Cragg GM, Herald DL, Takada T, Iwamoto C et al. (2000) Isolation and structures of schleicherastatins 1-7 and schleicheols 1 and 2 from the teak forest medicinal tree Schleichera oleosa. J Nat Prod 63, 72-8.   DOI   ScienceOn
18 Akihisa T, Yasukawa K, Yamaura M, Ukiya M, Kimura Y, Shimizu N et al. (2000) Triterpene alcohol and sterol ferulates from rice bran and their anti-inflammatory effects. J Agric Food Chem 48, 2313-9.   DOI   ScienceOn