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http://dx.doi.org/10.3839/jabc.2013.035

Effect of Cheonggukjang Made from Sword Bean on Serum Lipid Profile and Tissue Change in Rats  

Kim, Jae-Young (Pesticide and Veterinary Drug Residues Division, Department of Food Safety Evaluation, National Institute of Food and Drug Evaluation, Ministry of Food and Drug Safety)
Kim, Un-Sung (Quality Improvement Evaluation Team, Korea Health Industry Development Institute)
Chang, Moon-Ik (Pesticide and Veterinary Drug Residues Division, Department of Food Safety Evaluation, National Institute of Food and Drug Evaluation, Ministry of Food and Drug Safety)
Moon, Kwang-Hyun (Health Care Team, Sunchang County Office)
Baek, Seung-Hwa (Department of Biofood Science and Biotechnology, Chungbuk Provincial University)
Publication Information
Journal of Applied Biological Chemistry / v.56, no.4, 2013 , pp. 219-227 More about this Journal
Abstract
This study was to investigate serum triglyceride (TG), phospholipid (PL), and cholesterol concentrations after feeding the combined diets of prepared traditional Cheonggukjang (TC) or Cheonggukjang made from sword bean powder (CS), the feed, and high-fat cholesterols at certain ratio for 8 weeks in rats, and then confirmed the effects of the diets based on the changes in the tissues of livers, kidneys, and spleens. The serum TG concentrations were lower in CS group compared to that of in TC group. The increase of PL concentrations was greater in CS group than that of TC group. FChCS6 group (92% feed+2% cholesterol+6% CS) showed the lowest total-cholesterol (T-C), $60.1{\pm}8.5mg/dL$, indicating that CS was effective to lower the T-C. Both TG/PL and T-C/PL ratio tended to be decreased. As CS intake was effective in the reduction of low density lipoprotein-cholesterol level as well as the increase of high density lipoprotein-cholesterol level, it would be effective in the prevention of adult diseases and circulatory diseases. It was confirmed that there were no changes in organ appearance and tissues in the rats with CS intake. Therefore, CS intake showed superior functionalities than that of TC intake.
Keywords
lipid profile; rat; serum; sword bean Cheonggukjang; tissue;
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Times Cited By KSCI : 4  (Citation Analysis)
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