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http://dx.doi.org/10.3839/jabc.2011.066

Isolation and Identification of Lipids from the Fruits of Acanthopanax sessiliflorus  

Kim, Su-Yeon (Graduate School of Biotechnology & Department of Oriental Medicinal Materials and Processing, Kyung Hee University)
Lee, Dae-Young (Graduate School of Biotechnology & Department of Oriental Medicinal Materials and Processing, Kyung Hee University)
Seo, Kyeong-Hwa (Graduate School of Biotechnology & Department of Oriental Medicinal Materials and Processing, Kyung Hee University)
Rho, Young-Deok (Graduate School of Biotechnology & Department of Oriental Medicinal Materials and Processing, Kyung Hee University)
Kim, Gye-Won (Brewing Research Center, Hankyung National University)
Cheoi, Dae-Sung (Jeongseon Agricultural Extension Center)
Baek, Nam-In (Graduate School of Biotechnology & Department of Oriental Medicinal Materials and Processing, Kyung Hee University)
Publication Information
Journal of Applied Biological Chemistry / v.55, no.2, 2012 , pp. 103-107 More about this Journal
Abstract
Acanthopanax sessiliflorus Seeman fruits (Araliaceae) were extracted at room temperature with 70% aqueous ethanol (EtOH). The concentrated extract was partitioned with ethyl acetate (EtOAc), n-butyl alcohol, and $H_2O$, successively. From the EtOAc fraction, four compounds were isolated through the repeated silica gel and octadecyl silica gel (ODS) column chromatographies. According to the results of physico-chemical and spectroscopic data including NMR, IR, and gas chromatography/mass spectrometer, the chemical structures of the compounds were determined as stigmasterol (1), linoleic acid (2), ${\beta}$-sitosterol (3), and stigmast-5-en-$3{\beta}$,$7{\beta}$-diol (4).
Keywords
Acanthopanax sessiliflorus; linoleic acid; NMR; ${\beta}$-sitosterol; stigmasterol; stigmast-5-en-$3{\beta}$,$7{\beta}$-diol;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
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1 Lee DY, Lee SJ, Kwak HY, Jung LK, Heo JE, Hong SY et al. (2009) Sterols Isolated from Nuruk (Rhizopus oryzae KSD-815) inhibit the migration of cancer cells. J Microbiol Biotechnol 19, 1328-32.   과학기술학회마을
2 Lee SH, Kim BK, Cho SH, and Shin KH (2002) Phyrochemical constituents from the fruits of Acanthopanax sessiliflorus. Arch Pharm Res 25, 280- 4.   DOI   ScienceOn
3 Lee SH, Lee YS, Jung SH, Ji J, Shin KH, Kim BK et al. (2003) Antitumor and immunostimulating activities of Acanthopanax sessiliflorus fruits. Nat Prod Sci 9, 112-6.   과학기술학회마을
4 Lee WT (1979) Distribution of Acanthopanax plants in Korea. Korean J Pharmacol 10, 103-7.   과학기술학회마을
5 Lee WT (1996) In Lineamenta Florae Korea (vol. 770). Academy CO, Korea.
6 Ryoo HS, Park SY, Chang SY, and Yook CS (2003) Triterpene components from the leaves of Acanthopanax sessiliflorus Seem. Korean J Pharmacogn 34, 269-73.   과학기술학회마을
7 Song MS, Lee YW, and Kim JD (2003) Extraction of Acanthopanax senticosus by supercitical fluid. Hwahak Konghak 41, 207-12.   과학기술학회마을
8 Brekhman II and Dardmov IV (1969) New substances of plant origin which increase nonspecific resistance. Annu Rev Pharmacol 9, 419-30.   DOI   ScienceOn
9 Choi JM, Kim KY, Lee SH, and Ahn JB (2011) Functional properties of water extracts from different parts of Acanthopanax sessiliflorus. Food Engineering Progress 15, 130-5.
10 Ghorab AH, Mahgoub MH, and Bekheta M (2006) Effect of some bioregulators on the chemical composition of essential oil and its antioxidant activity of Egyptian carnation (Dianthus caryophyllus L.). J Essent Oil-Bearing Plants 9, 214-22.   DOI
11 Glisic SB, Misic DR, Stamenic MD, Zizovic IT, Asanin RM, and Skala DU (2007) Supercritical carbon dioxide extraction of carrot fruit essential oil: chemical composition and antimicrobial activity. Food Chem 105, 346- 52.   DOI   ScienceOn
12 Habib MR, Nikkon F, Rahman M, Haque ME, and Karim MR (2007) Isolation of stigmasterol and beta-sitosterol from methanolic extract of root bark of Calotropis gigantea (Linn). Pakistan J Biol Sci 10, 4174-6.   DOI
13 Hyun JW, Yang YM, Sung MS, Chung HS, Paik WH, Kang SS et al. (1996) The Cytotoxic activity of sterol derivatives from Pulsatilla chinensis regal. J Korean Cancer 28, 145-50.
14 Akino N (1975) Antioxidants from Rape (Brassica campestris var. japonica Hara) oil cake. Nat Prod RES 18, 231-9.
15 Jeong SC, Jeong YT, Yang BK, and Song CH (2006) Chemical characteristics and immuno-stimulating properties of biopolymers extracted from Acanthopanax sessiliflorus. Biochem Molecular Biol 39, 84-90.   과학기술학회마을   DOI
16 Jing JL, Lee SH, Lee YY, Kim JM, Heo JE, and Yun-Choi HS (2004) Platelet anti-aggregating triterpenoids from the leaves of Acanthopanax senticosus and the fruits of A. sessiliflorus. Planta Medica 70, 564-6.   DOI   ScienceOn
17 Kwak HY, Lee SJ, Lee DY, Jung LK, Bae NH, Hong SY et al. (2008) Cytotoxic and anti-inflammatory activities of lipids from the Nuruk (Rhizopus oryzae KSD-815). J Korean Soc Appl Biol Chem 51, 142-7.   과학기술학회마을
18 Ahn JK, Park SY, Lee WY, and Lee JJ (2005) Effects of growth regulators on adventitious root growth and eleutherosides and chlorogenic acid accumulation in air lift bioreactor culture of Eleutherococcus koreaum. Korean J Plant Biotechnol 32, 57-61.   DOI   ScienceOn