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http://dx.doi.org/10.3839/jabc.2011.052

The Antifungal Activity of Bee Venom against Dermatophytes  

Yu, A-Reum (Department of Medical Biotechnology, SoonChunHyang University)
Kim, Jum-Ji (Department of Medical Biotechnology, SoonChunHyang University)
Park, Gil-Sun (Department of Medical Biotechnology, SoonChunHyang University)
Oh, Su-Mi (DongSung Pharm. Co., Ltd.)
Han, Chung-Sub (DongSung Pharm. Co., Ltd.)
Lee, Mi-Young (Department of Medical Biotechnology, SoonChunHyang University)
Publication Information
Journal of Applied Biological Chemistry / v.55, no.1, 2012 , pp. 7-11 More about this Journal
Abstract
The antifungal activities of the bee venom against Trichophyton mentagrophytes and Trichophyton rubrum were determined by using modified broth dilution assay. The most common dermatophytes, named T. mentagrophytes and T. rubrum, were known to cause a variety of cutaneous infections in humans and animals. The bee venom exhibited prominent antifungal activities against the two dermatophytes tested in this investigation. Moreover, the antifungal activities of the bee venom were much stronger than that of fluconazole, one of the commercial antifungal drugs used in the treatment and prevention of superficial and systemic fungal infections. The result suggests that bee venom could be developed as a natural antifungal drug.
Keywords
antifungal activity; bee venom; Trichophyton mentagrophytes; Trichophyton rubrum;
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