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http://dx.doi.org/10.3839/jabc.2010.038

Antioxidant and Antibacterial Activities, and Tyrosinase and Elastase Inhibitory Effect of Fermented Omija (Schizandra chinensis Baillon.) Beverage  

Cho, Eun-Kyung (Department of Bio-Food Materials, College of Medical Life Sciences, Silla University)
Cho, Hea-Eun (Department of Food and Nutrition, College of Medical Life Sciences, Silla University)
Choi, Young-Ju (Department of Food and Nutrition, College of Medical Life Sciences, Silla University)
Publication Information
Journal of Applied Biological Chemistry / v.53, no.4, 2010 , pp. 212-218 More about this Journal
Abstract
This study was aimed to investigate the contents of chemical components and the biological activity of fermented Omija (Schizandra chinensis Baillon.) beverage (FOB), which have not been well known up to now. General compositions and the contents of mineral and vitamin of FOB were lower than Omija before fermentation (OBF). In addition, most sucrose was digested into glucose and fructose in FOB. This suggests that the beneficial contents may be made from general compositions by fermentation, though more evidences are needed. Antioxidant activity of FOB was measured by using 2,2-diphenyl-l-picryl-hydrazyl (DPPH) free radical scavenging activity and superoxide dismutase-like activity (SODA). DPPH radical scavenging activity and SODA were increased in a dose-dependent manner, and were about 79.7% and 60.8% at four times diluted FOB (25% of FOB), respectively. The FOB also showed strong antibacterial activity on Escherichia coli. Beauty effect of FOB was demonstrated by the analysis of tyrosinase and elastase inhibitory activities, and they were remarkably increased in a dose-dependent manner. Tyrosinase inhibitory activity was about 82% at two times diluted FOB (50% of FOB) and elastase inhibitory activity was 78.2% at five times diluted FOB (20% of FOB). These results suggest that FOB has a strong antioxidant activity, and tyrosinase and elastase inhibitory effects.
Keywords
antibacterial activity; antioxidant activity; elastase inhibitory activity; Schizandra chinensis Baillon; tyrosinase inhibitory activity;
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Times Cited By KSCI : 13  (Citation Analysis)
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1 Zhu M, Lin KF, Yeung RY, and Li RC (1999) Evaluation of the protective effects of Schizandra chinensis on Phase I drug metabolism using a CCl4 intoxication model. J Ethnopharmacol 67, 61-68.   DOI   ScienceOn
2 James AEK, Timothy DW, and Gorden L (1996) Inhibition of human leujocyte and porcine pancreatic elastase by homologues of bovine pancreatic tyrosinase inhibitors. Biochemistry 35, 9090-9096.   DOI   ScienceOn
3 Jeong PH, Kim YS, and Shin DH (2006) Changes of physicochemical characteristics of Schizandra chinensis during postharvest ripening at various temperatures. Korean J Food Sci Technol 38, 469-474.   과학기술학회마을
4 Doh ES, Chang JP, Lee KH, and Seong NS (2010) Ginsenoside change and antioxidation activity of fermented ginseng. Korean J Medicinal Crop Sci 18, 255-265.   과학기술학회마을
5 Hsu HY, Chen YP, Shen SJ, Hsu CS, Chen CC, and Chang HC (1986) Oriental matieria Medica. Oriental Healing Arts Institute, pp. 624. California, USA.
6 Hyun KH, Kim HJ, and Jeong HC (2002) A study on determining chemical compositions of Schizandra chinensis. Korean J Plant Res 15, 1-7.   과학기술학회마을
7 Ip SP, Che CT, and Ko KM (1998) Structure activity relationship of Schizandrins in enhancing liver mitochondrial glutathione status in $CCl_4$-poisoned mice. Zhongguo Yao Li Xue Bao 19, 313-316.
8 Choi OK, Kim YS, Cho GS, and Sung CK (2002) Screening of antimicrobial activity from Korean plants. Korean J Food Nutr 15, 300-306.   과학기술학회마을
9 Cho HE, Choi YJ, and Cho EK (2010) Antioxidant and nitrite scavenging activity, and $\alpha$-glucosidase inhibitory effect of water extract from Schizandra chinensis Baillon. J Korean Soc Food Sci Nutr 39, 481-486.   DOI   ScienceOn
10 Cho YJ, Ju IS, Kim BC, Lee WS, and Kim MJ (2007) Biological activity of Omija (Schizandra chinensis Baillon) extracts. Korean J Appl Biol Chem 50, 198-203.   과학기술학회마을
11 DeWitt DL, Rollins T, Day JS, Gauger JA, and Smith WL (1981) Orientation of the active site, and antigenic determinants of prostaglandin endoperoxide of synthase in the endoplasmic reticulum. J Biol Chem 256, 10375-10382.
12 Marklund S and Marklund G (1975) Involvement of superoxide aminoradical in the oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47, 468-474.
13 Blois MS (1958) Antioxidant determination by the use of a stable free radical. Nature 26, 1198-1200.
14 Tsuji N, Moriwaki S, Suzuki Y, Takema Y, and Imokawa G (2001) The role of elastase secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity. Photochem Photobiol 74, 283-290.   DOI   ScienceOn
15 Yagi A, Kanbara T, and Morinobu N (1987) Inhibition of mushroom tyrosinase by aloe extract. Planta Medica 53, 517-519.   DOI   ScienceOn
16 Ying QL, Rinehart AR, Simon SR, and Cheronis JC (1991) Inhibition of human leucocyte elastase by ursolic acid; evidence for a binding site for pentacyclic. Biochem J 277, 521-526.   DOI
17 Nam KA (2007) Characterization of squid sjin collagens and functionality of their enzymatic hydrolysates. MS Thesis, Gangneung National University, Gangwon, Korea.
18 Park MS, Rim YS, and Shin SC (2006) Comparison of the properties and extracting conditions of juice preparation from Schizandra nigar. J Korean Forestry Soc 95, 453-485.
19 Piddock LJV (1990) Techniques used for the determination of antimicrobial resistance and sensitivity in bacteria. J Appl Bacteriol 68, 307-310.   DOI
20 Lim JD, Yu CY, Kim MJ, Yun SJ, Lee SJ, Kim NY, and Chung IM (2004) Comparision of SOD activity and phenolic compound contents in various Korean medicinal plants. Korean J Medicinal Crop Sci 12, 191-202.   과학기술학회마을
21 Min SH and Oh HS (2000) A study on the properties of hot water extracts of Korean dried tangerine peel and development of beverage by using it. Korean J Soc Food Cookery 18, 51-56.
22 Korea Food and Drug Administration (2005) Food Standards Codex. Korean Foods Industry Association, Seoul, Korea.
23 Mok CK (2005) Quality characteristics of instant tea prepared from spray-dried Omija (Schizandra chinensis Baillon) extract grape juice mixture. Food Engineer Prog 9, 226-230.
24 Molokovskii DS, Davydov VV, and Tiulenev VV (1987) The action of adaptogenic plant preparations in experimental alloxan diabetes. Probi Endokrinol 35, 82-87.
25 Kim YC, Cho CW, Rhee YK, Yoo KM, and Rho JH (2007) Antioxidant activity of ginseng extracts prepared by enzyme and heat treatment. J Korean Soc Food Sci Nutr 36, 1482-1485.   과학기술학회마을   DOI   ScienceOn
26 Lee HW, Shin DH, and Lee WC (1998) Morphological and chemical characteristics of Mulberry (Morus) fruit with varieties. Korean J Seric Sci 40, 1-7.
27 Kim NM, Lee JW, Do JH, and Yang JW (2003) Effects of the fermentation periods on the qualities and functionalities of the fermentation broth of wild vegetables. Kor J Food Sci Technol 35, 272-279.   과학기술학회마을
28 Lee JS, Lee MG, and Lee SW (1989) A study on the general components and minerals in parts of Omija. Korean J Dietary Culture 4, 173-176.
29 Kim JW, Kim DK, Park JS, Lee YK, Beik KY, and Kim SD (2009) Antioxidant and antimicrobial activities of shark collagens, and inhibitory actions on elastase and tyrosinase. Korean J Food Preserv 16, 419-426.   과학기술학회마을
30 Kim MJ, Kim JY, Choi SW, Hong JT, and Yoon KS (2004) Antiwrinkle effect of Safflower (Cathamustinctorius) seed extract. J Soc Cosmet Sci Korea 30, 15-22.   과학기술학회마을
31 Kim JH, Park JH, Park SD, Choi SY, Seong JH, and Hoon KD (2002) Preparation and antioxidant activity of health drink with extract powders from Carthamus tinctorius L. seed. Korean J Food Sci Technol 34, 617-624.   과학기술학회마을
32 Jung SW, Lee NY, Kim SJ, and Han DS (1995) Screening of tyrosinase inhibitor from plants. Korean J Food Sci Technol 27, 891-896.