Browse > Article

Antibacterial and Radical Scavenging Activities of 1-C-(p-Hydroxyphenyl)-Glycerol from Trichosanthes kirilowii  

Jang, Ki-Chang (National Institute of Subtropical Agriculture, R.D.A.)
Lee, Jin-Hwan (Yeongnam Agricultural Research Institute, National Institute of Crop Science, R.D.A.)
Kim, Seong-Cheol (National Institute of Subtropical Agriculture, R.D.A.)
Song, Eun-Young (National Institute of Subtropical Agriculture, R.D.A.)
Ro, Na-Young (National Institute of Subtropical Agriculture, R.D.A.)
Moon, Doo-Young (National Institute of Subtropical Agriculture, R.D.A.)
Um, Yeong-Cheol (National Institute of Subtropical Agriculture, R.D.A.)
Park, Ki-Hun (Division of Applied Life Science (BK21 Program), Environmental Biotechnology National Core Research Center, Research Institute of Life Science, Gyeongsang National University)
Publication Information
Journal of Applied Biological Chemistry / v.50, no.1, 2007 , pp. 17-21 More about this Journal
Abstract
1-C-(p-Hydroxyphenyl)-glycerol (1) was isolated and purified by column chromatography and recrystallization from the rhizome of Trichosanthes kirilowii, firstly in this species. Isolated compound showed inhibitory effects on the growth of five bacteria (Bacillus cereus, Escherichia coli, Streptococcus faecalis, etc) completely at the concentration higher than 10 ppm as well as delayed the growth of three bacteria (Bacillus substilis, Staphylococcus aureus, Pseudomonas aeroginosa) at the concentration of 25 ppm for 60 h. Moreover, this compound showed potent antioxidant activity against DPPH radical ($IC_{50}$ = 56.0 ppm)
Keywords
antibacterial; antioxidant; 1-C-(p-hydroxyphenyl)-glycerol; DPPH; Trichosanthes kirilowii;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Lundgren LN, Shen Z, and Theander O (1985) Dilignol glycosides from Pinus massoniana lamb. Acta Chemica Scandi., Series B: Organic Chem and Biochem B39, 241-248
2 Braca A, De Tommasi N, Di Bari L, Pizza C, Politi M, and Morelli I (2001) Antioxidant principles from Bauhinia terapotensis. J Nat Prod 64, 892-895   DOI   ScienceOn
3 Piddok LJV (1990) Techniques used for the determination of antibacterial resistance and sensitivity in bacteria. J Appl Bacteriol 68, 307-318   DOI
4 Jiangsu New Medicinal College Edita (1986) The Dictionary of Chinese Materia Medica. Shanghai Science and Technology Press 1782
5 Otshudi AL, Foriers A, Vercruysse A, Van Zeebroeck A, and Lauwers S (1999) In vitro antimicrobial activity of six medicinal plants traditionally used for the treatment of dysentery and diarrhoea in Democratic Republic of Congo (DRC). Phytomedicine 7, 167-172
6 Essawi T and Srour M (2000) Screening of some Palestinian medicinal plants for antibacterial activity. J Ethnopharmacol 70, 343-349   DOI   ScienceOn
7 Lundgren LN, Popoff T, and Theander O. (1982) Arylglycerol glucides from Pinus sylvestris. Acta Chemica Scandi., Series B: Organic Chem and Biochem B36, 695-699
8 Namba T (1994) The Encyclopedia of Wakan-Yaku (Traditional Sino-Japanese Medicines) with Color Picture, I, Hoikusys, Osaka, Revised Edition, 271
9 Katakawa J, Tetsumi T, Kamei S, Iida T, and Katai M (2000) Phenolic compounds of fruit of Coix lachrymajobi L. Natural Medicines 54, 257-260
10 Kim JH, Lee DS, Lim CW, Park HY, and Park JH (2002) Antibacterial activity of sea-mustard, Laminaria japonica extracts on the cariogenic bacteria, Streptococcus mutans. Korean J Fish Soc 35, 191-195
11 Lee HO, Baek SH, and Han DM (2001) Antimicrobial effects of Chamaecyparis obtusa essential oil. Korean J Microbiol Biotechnol 29, 253-257   과학기술학회마을
12 Brand-Williams W, Cuvelier ME, and Berset C (1995) Use of a free radical method to evaluate antioxidant activity. Lebensm Wiss Technol 28, 25-30   DOI
13 Mead PS, Slutsker L, Dietz V, McCaig LF, Breese JS, Shapiro C, Griffin PM, and Tauxe RV (1999) Food related illness and death in the United States. Emerg Infect Dis 5, 607-625   DOI
14 Blois MS (1958) Antioxidant determinations by the use of a stable free radical. Nature 181, 1199-1200   DOI   ScienceOn