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Soy Isoflavones and Soyasaponins: Characteristics and Physiological Functions  

Lee, Yoon-Bok (School of Agricultural Biotechnology and Center for Agricultural Biomaterials, College of Agrliculture and Life Sciences, Seoul National University)
Lee, Hyong-Joo (School of Agricultural Biotechnology and Center for Agricultural Biomaterials, College of Agrliculture and Life Sciences, Seoul National University)
Kim, Chung-Ho (Department of Food and Nutrition, Seowon University)
Lee, Soo-Bok (Research Institute of Food and Nutritional Sciences and Department of Food and Nutrition, Yonsei University)
Sohn, Heon-Soo (Central Research Institute, Dr. Chung's Food Co., Ltd.)
Publication Information
Journal of Applied Biological Chemistry / v.48, no.2, 2005 , pp. 49-57 More about this Journal
Abstract
Soy is an important food in Asia and many studies have suggested that the low incidences of chronic diseases in Asian countries are associated with diets that are rich in soy. Soy contains many kinds of phytochemicals, and soy isoflavones and soyasaponins have received considerable attention. Twelve isoflavone components have been isolated from soy: three aglycones (daidzein, genistein, and glycitein), and their respective nine glucosidic conjugates. Soy isoflavones are similar in structure to estrogen and exhibit both estrogenic and antiestrogenic activities. Soy isoflavones exhibit anticancer activity, can reduce the risk of cardiovascular disease, and are beneficial to brain and bone health. Soyasaponins are divided into three groups (A, B, and E saponins), and they exhibit hypocholesterolemic, anticancer, hepatoprotective, antioxidative, and anti-human-immunodeficiency-virus effects. Despite the abundant literature suggesting that soy isoflavones and soyasaponins have potential applications in preventive medicine, further research is needed to standardize dosages and ensure their efficacy.
Keywords
soy; chronic diseases; phytochemicals; isoflavones; soyasaponins; preventive medicine;
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