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http://dx.doi.org/10.3742/OPEM.2010.10.4.319

Structure elucidation of a newly isolated saponin from Clerodendrum serratum (L) Moon  

Bhujbal, Santosh S. (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research)
K.Nanda, Rabindra (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research)
S.Deoda, Ramesh (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research)
Kumar, Dinesh (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research)
Kewatkar, Shailesh M. (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research)
S.More, Laxmikant (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research)
J.Patil, Manohar (Marathawada Mitra Mandal's, College of Pharmacy)
Publication Information
Advances in Traditional Medicine / v.10, no.4, 2010 , pp. 319-321 More about this Journal
Abstract
Plant saponins are widely distributed amongst plants and have a wide range of biological properties. Icosahydropicenic acid, $C_{51}H_{80}O_{19}$ ((4S,6bS)-8a-((4,5-dihydroxy-6-methyl-3-((3R)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)carbonyl)-2-hydroxy-4, 6a, 6b, 11, 14b-pentamethyl-11-(2-methylprop-1-enyl)-3-(3,4,5-trihydroxy-6-(hydroxymethyl) - tetrahydro-2Hpyran-2-yloxy)-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicene-4-carboxylic acid), a new saponin was first time isolated from the roots of Clerodendrum Serratum (L) Moon (Verbenaceae). The structure elucidation of the compound was carried out by $^1H$ NMR and DART-MS studies.
Keywords
Clerodendrum serratum; DART-MS; Icosahydropicenic acid; plant saponin;
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