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Antioxidant and antidiabetic activities of extracts from Cirsium japonicum roots  

Yin, Jie (School of Biotechnology, Kangwon National University)
Heo, Seong-Il (School of Biotechnology, Kangwon National University)
Wang, Myeong-Hyeon (School of Biotechnology, Kangwon National University)
Publication Information
Nutrition Research and Practice / v.2, no.4, 2008 , pp. 247-251 More about this Journal
Abstract
This study investigated the antioxidant activity of methanol (MeOH) and water extracts from roots of Cirsium japonicum in vitro, MeOH extract showed a stronger tree radical scavenging activity than water extract. However, both of extracts showed a concentration dependent hydroxyl radical scavenging activity, reducing power and metal chelating ability, MeOH extract had greater phenolic and flavonoid contents than water extract. The antidiabetic activity of these two extracts was evaluated by the a-glucosidase inhibition assay, The water extract showed a considerable a-glucosidase inhibitory activity. To our knowledge, this may be the first time to report the antioxidant and antidiabetic activities in Cirsium japonicum roots.
Keywords
Cirsium japonicum; antioxidant; antidiabetic; methanol and water extracts;
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