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Synthesis of New pH-Sensitive Poly(ethylene oxide-b-maleic acid) from Modification of Poly(ethylene oxide-b-N-phenylmaleimide)  

Go, Da-Hyeon (Department of Chemistry, Kyunghee University)
Jeon, Hee-Jeong (Department of Chemistry, Kyunghee University)
Kim, Tae-Hwan (Department of Chemistry, Kyunghee University)
Kim, Geun-Seok (Department of Chemistry, Kyunghee University)
Choi, Jin-Hee (Department of Chemistry, Kyunghee University)
Lee, Jae-Yeol (Department of Chemistry, Kyunghee University)
Kim, Jung-Ahn (Department of Chemistry, Kyunghee University)
Yoo, Hyun-Oh (Department of Chemical Engineering, Hanyang University)
Bae, You-Han (Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah)
Publication Information
Macromolecular Research / v.16, no.7, 2008 , pp. 659-662 More about this Journal
Abstract
A new and useful poly(ethylene oxide)-based pH-sensitive block copolymer is introduced. Poly(ethylene oxide-b-N-phenylmaleimide) was first synthesized by anionic polymerization of N-phenylmaleimide (N-PMI) using mixed alkali metal polymeric alkoxide by sequential monomer addition method in the mixture of benzene/THF/DMSO (10/5/3, v/v/v) at room temperature. Reductive deimidation of the resulting block copolymer was performed using hydrazine monohydrate leading to the formation of the corresponding pH-sensitive poly(ethylene oxide-b-maleic acid).
Keywords
pH-sensitive block copolymer; poly(ethylene oxide-b-maleic acid); anionic polymerization; modification;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 1  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
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