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Temperature Controllable HPLC Column for Preparative Fractionation of Polymers  

Im, Kyu-Hyun (Department of Chemistry and Polymer Research Institute, Pohang University of Science and Technology)
Park, Hae-Woong (Department of Chemistry and Polymer Research Institute, Pohang University of Science and Technology)
Kim, Young-Tak (Department of Chemistry and Polymer Research Institute, Pohang University of Science and Technology)
Chang, Tai-Hyun (Department of Chemistry and Polymer Research Institute, Pohang University of Science and Technology)
Publication Information
Macromolecular Research / v.16, no.6, 2008 , pp. 544-548 More about this Journal
Abstract
An HPLC column with a self-contained temperature control device was constructed for preparative temperature programmed interaction chromatography. Two Peltier plates were attached to a large bore column ($120{\times}22\;mm$ i.d.) and the column temperature was controlled by PID mode feed back control. At a flow rate of 1.5 mL/min, the column temperature could be increased and decreased at a rate as high as $50^{\circ}C/min$ and $10^{\circ}C/min$, respectively, which is much faster than using a column jacket and bath/circulator. The rapid heating and cooling rates allows a high repetition rate of chromatographic fractionation. The performance of the temperature controllable column was demonstrated successfully by the fractionation of homo-polymer precursors from diblock copolymers.
Keywords
polymer fractionation; HPLC column; temperature control; Peltier device; temperature gradient interaction chromatography;
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Times Cited By Web Of Science : 4  (Related Records In Web of Science)
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