Browse > Article

Plasma Protein Adsorption to Anion Substituted Poly(vinyl alcohol) Membranes  

Ryu, Kyu-Eun (Department of Biomedical Sciences, College of Medicine, Catholic University)
Hyangshuk Rhim (Department of Biomedical Sciences, Department of Internal Medicine, College of Medicine, Catholic University)
Park, Chong-Won (Division of Hematology, Department of Internal Medicine, Department of Internal Medicine, College of Medicine, Catholic University)
Chun, Heung-Jae (Department of Biomedical Sciences, Department of Internal Medicine, College of Medicine, Catholic University)
Hong, Seung-Hwa (Blood Products Division, Biologics Evaluation Department, Korea Food and Drug Administration)
Kim, Jae-Jin (Biomaterials Research Center, Korea Institute of Science and Technology)
Lee, Young-Moo (School of Chemical Engineering, College of Engineering, Hanyang University)
Publication Information
Macromolecular Research / v.11, no.6, 2003 , pp. 451-457 More about this Journal
Abstract
Anion-substituted poly(vinyl alcohol) (PVA) membranes, carboxymethylated PVA (C-PVA), and sulfonated PVA (S-PVA) were prepared and the effects of these substitutions on the plasma protein adsorption were studied by one- and two-dimensional gel electrophoresis and immunoblotting. When Cuprophane was used as a negative control, the amount of total proteins bound to samples decreased in the order Cuprophane > PVA > C-PVA > S-PVA, which we attribute to the effects of the surface characteristics of the samples, such as their surface tensions and electrostatic properties, on the adsorption of proteins to the surfaces of the materials. The results revealed that albumin was the most abundant protein in all the samples. The proportion of adsorbed fibrinogen to S-PVA exceeded those of PVA and C-PVA, whereas S-PVA exhibited the lowest IgG adsorption affinity among the samples we studied.
Keywords
carboxymethylated poly(vinyl alcohol); sulfonated poly(vinyl alcohol); hemodialysis membrane; plasma protein adsorption;
Citations & Related Records

Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 4
연도 인용수 순위
1 /
[ P.M.Galletti;C.K.Colton;M.J.Lysaght;J.D.Bronzino(ed.) ] / The Biomedical Engineering Handbook
2 /
[ J.D.Andrade ] / Principles of Protein Adsorption in Surface and Interfacial Aspects of Biomedical Polymers
3 /
[ H.J.Chun;J.J.Kim;K.Y.Kim ] / Polymer J.   DOI
4 /
[ S.M.Slack;J.L.Bohnert;T.A.Horbett ] / Ann. N. Y. Acad. Sci.   DOI   ScienceOn
5 /
[ J.Wettero;A.Askeudal;T.Bengtsson;P.Tengvall ] / Biomaterials   DOI   ScienceOn
6 /
[ S.Parzer;P.Balcke;C.Mannhalter ] / J. Biomed. Mater. Res.   DOI   ScienceOn
7 /
[ S.R.Mulzer;J.L.Brash ] / J. Biomed. Mater. Res.   DOI
8 /
[ M.C.Tanzi;M.Muttoni;R.Fumero;S.Scuri;G.Cairo;C.Migliaresi (ed.) ] / Polymers in Medicine Ⅲ
9 /
[ S.K.Min;J.H.Kim;D.J.Chung ] / Korea Polym. J.
10 /
[ A.C.Duncan;M.V.Sefton;J.L.Brash ] / Biomaterials   DOI   ScienceOn
11 /
[ L.Vroman ] / Bull. N.Y. Acad. Med.
12 Protein Adsorption on Biomaterials in Biomaterials: Interfacial Phenomena and Applications /
[ T.A.Horbett;S.L.Cooper(ed.);N.A.Peppas(ed.) ] / ACS Advances in Chemistry Series, ACS
13 /
[ K.C.Hong;J.H.Kim;J.Y.Bae ] / Korea Polym. J.
14 /
[ G.Khang;M.K.Choi;J.M.Rhee;S.J.Lee;H.B.Lee;Y.Iwasaki;N.Nakabayashi;K.Ishihara ] / Korea Polym. J.
15 /
[ M.Kiremitci;E.Gok;S.Ates ] / J. Biomater. Sci. Polym.(ed.)
16 /
[ J.P.Santerre;N.H.Vanderkaup;J.L.Brash ] / J. Biomed. Mater. Res.   DOI
17 /
[ D.Wessel;U.I.Flugge ] / Anal. Biochem.   DOI   ScienceOn
18 /
[ J.H.Lee;H.W.Kim;P.K.Pak;S.S.Kim;H.B.Lee ] / Korea Polym. J.
19 /
[ S.Y.Nam;H.J.Chun;Y.M.Lee ] / J. Appl. Polym. Sci.   DOI   ScienceOn
20 /
[ W.Breemhar;E.Brinkman;D.J.Elleus;T.Bengeling;A.antjes ] / Biomaterials   DOI   ScienceOn
21 /
[ D.K.Han;K.D.Park;G.H.Ryu;U.Y.Kim;B.G.Min;Y.H.Kim ] / J. Biomed. Mater. Res.   DOI
22 /
[ D.Owens ] / J. Appl. Polym. Sci.
23 /
[ A.Gessner;A.Lieske;B.R.Paulke;R.H.Muller ] / Eur. J. Pharm. Biopharm.   DOI   ScienceOn
24 /
[ E.J.Harfenist;M.A.Packham;J.F.Mustard ] / Blood
25 /
[ A.Finch ] / Poly(vinyl alcohol)-Development
26 /
[ T.Sugiyama;M.Okuma;F.Ushikubi;S.Seusaki;K.Kanaji;H.Uchino ] / Blood
27 /
[ H.J.Chun;J.J.Kim;S.H.Lee;K.Y.Kim;U.Y.Kim ] / Polymer J.   DOI
28 /
[ Y.Ikada;H.Iwata;F.Horii;T.Matsunaga;M.Tanigushi;M.Suzuki ] / J. Biomed. Mater. Res.   DOI   ScienceOn
29 /
[ I.Roitt;J.Brostoff;D.Male ] / Immunology, (<tex>$5^{th}$</TEX> ed.)
30 /
[ U.K.Laemmli ] / Nature   DOI   ScienceOn
31 /
[ T.G.Grasel;S.L.Cooper ] / J. Biomed. Mater. Res.
32 /
[ M.Berger;B.Broxup;M.V.Sefton ] / J. Mater. Sci.