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http://dx.doi.org/10.5478/MSL.2011.2.3.073

An anomalous dissociation of protonated cluster ions of DNA guanine-cytosine base-pair  

Seong, Yeon-Mi (Department of Chemistry, Sogang University)
Han, Sang-Yun (Center for Nano-bio Convergence Research, Korea Research Institute of Standards and Science (KRISS))
Jo, Sung-Chan (LCD R&D Center, LCD Division, Samsung Electronics, Co., Ltd.)
Oh, Han-Bin (Department of Chemistry, Sogang University)
Publication Information
Mass Spectrometry Letters / v.2, no.3, 2011 , pp. 73-75 More about this Journal
Abstract
In the collisionally-activated dissociation of the proton-bound cluster ions of DNA base guanine (G) and cytosine (C), $G{\bullet}{\bullet}H^+{\bullet}{\bullet}C$, the abundance of [$CH^+$] ions was found to be higher than that of [$GH^+$] despite the fact that G has a higher proton affinity than C. This unexpected observation seems to demonstrate another example that the simple kinetic method scheme does not work. We suggest that a kinetic factor or detailed dynamics governing the proton transfer and dissociation should be carefully considered in the applications of the kinetic method to the proton affinity measurements.
Keywords
Pronton affinity; Collisional dissociation; Proton transfer; Guanine; Cytosine;
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