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http://dx.doi.org/10.4283/JMAG.2016.21.4.599

Hard Tissue Analysis of NMR after Fluoride Administration  

Kim, Hye-Young (Dept. of Dental Hygiene, Kangwon National University)
Nam, Seoul-Hee (Dept. of Dental Hygiene, Kangwon National University)
Han, Man-Seok (Dept. of Radiological Science, Kangwon National University)
Publication Information
Journal of Magnetics / v.21, no.4, 2016 , pp. 599-602 More about this Journal
Abstract
Fluoride (F) is an important element for the mineralization of body tissues. The purpose of this study was to administer fluoride prenatally to rats to evaluate its beneficial concentration for rat bone using microstructural analysis, to analyze its effect on the bone structure, and to evaluate the effect of its transfer through rat placenta. Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectrometry (NMR) were performed. The $^{19}F$ NMR and $^{31}P$ NMR signals suggested the existence of fluoride ions in the apatite lattice because the signals were caused by the fluoride ions that were coupled to the phosphate atoms and were affected in the phosphate phases other than the element phases in the apatite. Consequently, if it was not affected too much, the desirable concentration of prenatal fluoride treatment could have a helpful effect on the bone crystal structure through placental fluoride transfer.
Keywords
Fourier transform infrared spectroscopy (FTIR); nuclear magnetic resonance spectrometry (NMR); microstructural analysis;
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  • Reference
1 W. L. Babeaux and I. Zipkin, J. Oral. Ther. Pharmacol. 3, 124 (1966).
2 E. D. Eanes and J. L. Meyer, J. Dent. Res. 57, 617 (1978).   DOI
3 M. D. Grynpas, C. Rey, Bone. 13, 423 (1992).   DOI
4 A. Vieira, R. Hancock, H. Limeback, M. Schwartz, and M. Grynpas, J. Dent. Res. 82, 909 (2003).   DOI
5 C. A. Baud, J. M. Very, and B. Courvoisier, Bone. 9, 361 (1988).   DOI
6 Y. Sakong, J. Y. Kim, J. S. Song, Y. H. Kwon, and K. B. Song, J. Korean Acad. Dent. Health 27, 139 (2003).
7 J. Timanen, L. Alvila, P. Hirva, and T. T. Pakkanen, J. Mat. Sci. 9, 187 (1998).
8 M. I. Kay, R. A. Young, and A. S. Posner, Nature 204, 1050 (1964).   DOI
9 A. P. Lee, J. Klinowski, and E. A. Marseglia, J. Archae Sci. 22, 257 (1995).   DOI
10 M. E. Ebifegha, J. E. Harrison, K. G. McNeill, S. S. Krishnan, and J. Ssengabi, Int. J. Rad. Appl. Instrum. 37, 159 (1986).   DOI
11 N. Gelman and R. F. Code, Solid State Nucl. Magn. Reson. 143-4, 191 (1999).
12 Y. Pan, Solid State Nuclear Magn. Res. 5, 263 (1995).   DOI
13 W. S. Driscoll, J. Dent. Child 48, 109 (1981).
14 Y. Pan, Solid State Nuclear Magnetic Resonance 5, 263 (1995).   DOI
15 T. F. Collins, R. L. Sprando, T. N. Black, M. E. Shackelford, N. Olejnik, M. J. Ames, J. I. Rorie, and D. I. Ruggles, Food Chem. Toxicol. 39, 867 (2001).   DOI
16 A. S. Al-Hiyasat, A. M. Elbetiecho, and H. Darmani, Fluoride 33, 9 (2000).
17 E. D. Eanes and A. W. Hailer, Calcif. Tissue Int. 63, 250 (1998).   DOI
18 M. Iijima, D. G. Nelson, Y. Pan, A. T. Kreinbrink, M. Adachi, T. Goto, and Y. Moriwaki, Calcif. Tissue Int. 59, 377 (1996).   DOI
19 T. M. Marthaler, Oral. Health Prev. Dent. 1, 129 (2003).
20 E. T. Everett, M. A. McHenry, N. Reynolds, H. Eggertsson, J. Sullivan, C. Kantmann, E. A. Martinez-Mier, J. M. Warrick, and G. K. Stookey, J. Dent. Res. 81, 794 (2002).   DOI
21 J. J. Murray, Caries Res. 27, 2 (1993).   DOI
22 L. W. Ripa, J. Public Health Dent. 53, 17 (1993).
23 WHO. The health aspects of food and nutrition. A manual for developing countries in western pacific region, 3rd edition, Western Pacific Regional Office (1979) pp. 27-60.
24 S. Jones, B. A. Burt, P. E. Petersen, and M. A. Lennon, Bull. World Health Organ. 83, 670 (2005).
25 R. Caldera, J. Chavinie, J. Fermanian, D. Tortrat, and A. M. Laurent, Biol. Neonate 54, 263 (1988).   DOI