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http://dx.doi.org/10.4283/JMAG.2011.16.2.164

Evaluation of Magnetic and Thermal Properties of Ferrite Nanoparticles for Biomedical Applications  

Tomitaka, Asahi (Department of Electrical and Computer Engineering, Yokohama National University)
Jeun, Min-Hong (Biomagnetics Laboratory, Department of Electrical and Computer Engineering, National University of Singapore)
Bae, Seong-Tae (Biomagnetics Laboratory, Department of Electrical and Computer Engineering, National University of Singapore)
Takemura, Yasushi (Department of Electrical and Computer Engineering, Yokohama National University)
Publication Information
Journal of Magnetics / v.16, no.2, 2011 , pp. 164-168 More about this Journal
Abstract
Magnetic nanoparticles can potentially be used in drug delivery systems and for hyperthermia therapy. The applicability of $Fe_3O_4$, $CoFe_2O_4$, $MgFe_2O_4$, and $NiFe_2O_4$ nanoparticles for the same was studied by evaluating their magnetization, thermal efficiency, and biocompatibility. $Fe_3O_4$ and $CoFe_2O_4$ nanoparticles exhibited large magnetization. $Fe_3O_4$ and $NiFe_2O_4$ nanoparticles exhibited large induction heating. $MgFe_2O_4$ nanoparticles exhibited low magnetization compared to the other nanoparticles. $NiFe_2O_4$ nanoparticles were found to be cytotoxic, whereas the other nanoparticles were not cytotoxic. This study indicates that $Fe_3O_4$ nanoparticles could be the most suitable ones for hyperthermia therapy.
Keywords
magnetic nanoparticle; drug delivery systems; hyperthermia; cytotoxicity;
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1 M. Ma., Y. Wu, J. Zhou, Y. Sun, Y. Zhang, and N. Gu, J. Magn. Magn. Mater. 268, 33 (2004).   DOI   ScienceOn
2 P. Pradhan, J. Giri, G. Samanta, H. D. Sarma, K. P. Mishra, J. Bellare, R. Banerjee, and D. Bahadur, J. Biomed. Mater. Res. Part B: Appl. Biomater. 81B, 12 (2007).   DOI   ScienceOn
3 H. Yin, H. P. Too, and G. M. Chow, Biomaterials 26, 5818 (2005).   DOI   ScienceOn
4 T. Maehara, K. Konishi, T. Kamimori, H. Aono, H. Hirazawa, T. Naohara, S. Nomura, H. Kikkawa, Y. Watanabe, and K. Kawachi, J. Mater. Sci. 40, 135 (2005).   DOI
5 S. Bae, S. W. Lee, and Y. Takemura, Appl. Phys. Lett. 89, 252503 (2006).   DOI   ScienceOn
6 A. Tomitaka1, H. Kobayashi1, T. Yamada1, M. Jeun, S. Bae, and Y. Takemura, J. Phys.: Conf. Ser. 200, 122010 (2010).   DOI   ScienceOn
7 H. Kobayashi, A. Hirukawa, A. Tomitaka, T. Yamada, M. Jeun, S. Bae, and Y. Takemura, J. Appl. Phys. 107, 09B322 (2010).   DOI   ScienceOn
8 S. W. Lee, S. Bae, Y. Takemura, E. Yamashita, J. Kunisaki, S. Zurn, and C. S. Kim, IEEE Trans. Magn. 42, 2833 (2006).   DOI   ScienceOn
9 X. Huang and Z. Chen, J. Magn. Magn. Mater. 280, 37 (2004).   DOI   ScienceOn
10 V. Sepelak, I. Bergmann, D. Menzel, A. Feldhoff, P. Heitjans, F. J. Litterst, and K. D. Becker, J. Magn. Magn. Mater. 316, e764 (2007).   DOI   ScienceOn
11 A. Pardeep, P. Priyadharsini, and G. Chandrasekaran, J. Magn. Magn. Mater. 320, 2774 (2008).   DOI   ScienceOn
12 S. Balakrishnan, M. J. Bonder, and G. C. Hadjipanayis, J. Magn. Magn. Mater. 321, 117 (2009).   DOI   ScienceOn
13 N. Sadeghiani, L. S. Barbosa, L. P. Silva, R. B. Azevedo, P. C. Morais, and Z. G. M. Lacava, J. Magn. Magn. Mater. 289, 466 (2005).   DOI   ScienceOn
14 Q. A. Pankhurst, J. Connolly, S. K. Jones, and J. Dobson, J. Phys. D: Appl. Phys. 36, R167 (2003).   DOI   ScienceOn
15 H. Maeda, G. Y. Bharate, and J. Daruwalla, Eur. J. Pharm. Biopharm. 71, 409 (2009).   DOI   ScienceOn
16 H. Nathani and R. D. K. Misra, Mater. Sci. Eng. 94, 228 (2004).