Heterogeneity in liver histopathology is associated with GSK-3β activity and mitochondrial dysfunction in end-stage diabetic rats on differential diets |
Lee, Jun-Ho
(Department of Biochemistry, Konkuk University School of Medicine)
Choi, Soo-Bong (Department of Internal Medicine, Konkuk University Chungju Hospital, Konkuk University School of Medicine) Sung, Dong-Jun (Division of Sport and Health Studies, College of Biomedical and Health Science, Konkuk University) Jin, Mingli (Gachon Institute of Pharmaceutical Sciences, College of Pharmacy, Gachon University) Lee, Ju-Han (Department of Biochemistry, Konkuk University School of Medicine) Mun, Ji-Young (Department of Structure and Function of Neural Network, Korea Brain Research Institute) Hwang, Tae-Sook (Department of Pathology, Konkuk University School of Medicine) Han, Sang-Don (Department of Medical Education, Konkuk University School of Medicine) Ro, Young-Tae (Department of Biochemistry, Konkuk University School of Medicine) Kim, Sung-Young (Department of Biochemistry, Konkuk University School of Medicine) You, Jueng-Soo (Department of Biochemistry, Konkuk University School of Medicine) Lim, Inja (Department of Physiology, College of Medicine, Chung-Ang University) Noh, Yun-Hee (Department of Biochemistry, Konkuk University School of Medicine) |
1 | Lee JH, Lee JH, Jin M et al (2014) Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats. Exp Mol Med 46, e111 DOI |
2 | Lee JH, Choi SB, Jin M et al (2015) Euglycemia in Diabetic Rats Leads to Reduced Liver Weight via Increased Autophagy and Apoptosis through Increased AMPK and Caspase-3 and Decreased mTOR Activities. J Diabetes Res 2015, 497431 DOI |
3 | Prentki M and Nolan CJ (2006) Islet beta cell failure in type 2 diabetes. J Clin Invest 116, 1802-1812 DOI |
4 | Rahier J, Guiot Y, Goebbels RM et al (2008) Pancreatic beta-cell mass in European subjects with type 2 diabetes. Diabetes Obes Metab 10, 32-42 DOI |
5 | Halban PA, Polonsky KS, Bowden DW et al (2014) -cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care 37, 1751-1758 DOI |
6 | Nakamuta M, Ohashi M, Goto K et al (1993) Diabetes mellitus-associated glycogen storage hepatomegaly: report of a case and review of the Japanese literature. Fukuoka Igaku Zasshi 84, 354-358 |
7 | Chatila R and West AB (1993) Hepatomegaly and abnormal liver tests due to glycogenosis in adults with diabetes. Medicine (Baltimore) 75, 327-333 DOI |
8 | Van Steenbergen W and Lanckmans S (1995) Liver disturbances in obesity and diabetes mellitus. Int J Obes Relat Metab Disord 19, S27-S36 |
9 | Munns CF, McCrossin RB, Thomsett MJ et al (2000) Hepatic glycogenosis: reversible hepatomegaly in type 1 diabetes. J Paediatr Child Health 36, 449-452 DOI |
10 | Li SY, Fang CX, Aberle NS 2nd et al (2005) Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function. J Endocrinol 186, 491-503 DOI |
11 | Mariappan MM, Shetty M, Sataranatarajan K et al (2008) Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells. J Biol Chem 283, 30566-30575 DOI |
12 | Goodman MN and Ruderman NB (1980) Starvation in the rat. I. Effect of age and obesity on organ weights, RNA, DNA, and protein. Am J Physiol 239, E269-E276 |
13 | Singh R and Cuervo AM (2011) Autophagy in the cellular energetic balance. Cell Metab 13, 495-504 DOI |
14 | Petersen KF, Befroy D, Dufour S et al (2003) Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300,1140-1142 DOI |
15 | Smith BW and Adams LA (2011) Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment. Nat Rev Endocrinol 7, 456-465 DOI |
16 | Lewis GF, Carpentier A, Adeli K et al (2002) Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 23, 201-229 DOI |
17 | Ibdah JA, Perlegas P, Zhao Y et al (2005) Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance. Gastroenterology 128, 1381-1390 DOI |
18 | Rector RS, Thyfault JP, Uptergrove GM et al (2010) Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. J Hepatol 52, 727-736 DOI |
19 | Franko A, von Kleist-Retzow JC, Neschen S et al (2014) Liver adapts mitochondrial function to insulin resistant and diabetic states in mice. J Hepatol 60, 816-823 DOI |
20 | Adams LA, Harmsen S, St Sauver JL et al (2010) Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study. Am J Gastroenterol 105, 1567-1573 DOI |
21 | Roden M (2006) Mechanisms of Disease: hepatic steatosis in type 2 diabetes-pathogenesis and clinical relevance. Nat Clin Pract Endocrinol Metab 2, 335-348 DOI |
22 | Torbenson M, Chen YY, Brunt E et al (2006) Cummings, O.W.; Gottfried, M.; Jakate, S.; Liu. Y.C.; Yeh, M.M.; Ferrell, L. Glycogenic hepatopathy: an underrecognized hepatic complication of diabetes mellitus. Am J Surg Pathol 30, 508-513 DOI |
23 | Harrison SA. Brunt EM. Goodman ZD et al (2006) Diabetic hepatosclerosis: diabetic microangiopathy of the liver. Arch Pathol Lab Med 130, 27-32 DOI |
24 | Fioretto P, Mauer M, Brocco E et al (1996) Patterns of renal injury in NIDDM patients with microalbuminuria. Diabetologia 39, 1569-1576 DOI |
25 | Ekinci EI, Jerums G, Skene A et al (2013) Renal structure in normoalbuminuric and albuminuric patients with type 2 diabetes and impaired renal function. Diabetes Care 36, 3620-3626 DOI |
26 | Sharma SG, Bomback AS, Radhakrishnan J et al (2013) The modern spectrum of renal biopsy findings in patients with diabetes. Clin J Am Soc Nephrol 8, 1718-1724 DOI |